Research Interests Aquatic Toxicology Molecular Endocrinology Marine Biotechnology Environmental Policy Representative Publications (out of 78 full papers in peer-reviewed international journals, 4 book chapters and over 170 abstracts or proceeding papers presented in international conferences): 1. Yang, J., Zhu, J., and Chan, K.M. (2016) BDE-99, but not BDE-47, is a transient aryl hydrocarbon receptor agonist in zebrafish liver cells. Toxicol. Appl. Pharmacol. 305: 203-215. 2. Chen, Y.Y., and Chan, K.M. (2016) Modulation of the expression of estrogen receptor pathway related genes by TCDD, Cd2+ and mixtures of Cd2+ and TCDD in zebrafish. Chemosphere 147: 467-476. 3. Zhang, L., Li, Y., J.C. Yu, and Chan, K.M. (2015) A photothermally triggered and glutathione-responsive drug delivery platform through DNA/copper sulfide gates. Nanoscale 7(29): 12614-24. 4. Yang, J., and Chan, K.M. (2015) Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL. Aq. Toxicol. 159:138-147. 5. Chen, Y.Y., Zhu, J.Y., and Chan, K.M. (2014) Effects of cadmium on cell proliferation, apoptosis, and proto-oncogene expression in zebrafish liver cells. Aq. Toxicol. 157: 196-206. 6. Leung, K.P., Chen, D.S., and Chan, K.M. (2014) Understanding copper sensitivity in zebrafish (Danio rerio) through tissue expression profiles and intracellular localization of copper transporters. Metallomics 6: 1057-1067. 7. Chow, W.S., Chan, W. K-L., and Chan, K.M. (2013) Toxicities and vitellogenin gene expression in zebrafish embryos and larvae exposed to organochlorine pesticides, tetrabrominated bisphenol A, and bisphenol A. J. App. Toxicol. 33: 670-678. 8. Chan, W.K-L., and Chan, K.M. (2012) Effects of BDE-47, TBBPA and BPA on the hypothalamic-pituitary-thyroid axis in zebrafish embryo-larvae. Aq. Toxicol. 108:106-111. 9. Chen, D.S., Zhang, D., Yu, J.C., and Chan, K.M. (2011) Effects of Cu2O nanoparticle and CuCl2 on zebrafish larvae and a liver cell-line. Aq. Toxicol. 105:344-354. 10. Wan, G, and Chan, K.M. (2010) A study of somatolactin actions by ectopic expression in transgenic zebrafish larvae. J. Mol. Endocrinol. 45: 1-16.