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The neuroinflammatory program at SickKids has made important advances in changing the trajectory of outcomes in children with MS and other neuroinflammatory disorders. Together with a team of scientists, Dr. Yeh's team is investigating pharmacological agents and lifestyle factors such as physical activity that can repair the brains of youth with MS. In 2019, we showed longitudinal associations between levels of physical activity and depression and fatigue in youth with MS. We also developed and piloted a new app and program to improve physical activity, named ATOMIC. We developed this app in response to novel findings linking physical activity and outcomes in these youth, and new opportunities to overcome barriers to improving physical activity in teens. We recently received a grant from the National MS Society to perform a multi-center trial of the effect of this intervention on physical activity in youth with MS. We are also performing work on strategies that can repair myelin in patients with MS and other demyelinating syndromes. To this end, we have initiated a pilot feasibility trial evaluating the use of an agent, metformin, in youth with MS, which has been funded by the Ontario Institute of Regenerative Medicine.
The neuroinflammatory program at SickKids has made important advances in changing the trajectory of outcomes in children with MS and other neuroinflammatory disorders. Together with a team of scientists, Dr. Yeh's team is investigating pharmacological agents and lifestyle factors such as physical activity that can repair the brains of youth with MS. In 2019, we showed longitudinal associations between levels of physical activity and depression and fatigue in youth with MS. We also developed and piloted a new app and program to improve physical activity, named ATOMIC. We developed this app in response to novel findings linking physical activity and outcomes in these youth, and new opportunities to overcome barriers to improving physical activity in teens. We recently received a grant from the National MS Society to perform a multi-center trial of the effect of this intervention on physical activity in youth with MS. We are also performing work on strategies that can repair myelin in patients with MS and other demyelinating syndromes. To this end, we have initiated a pilot feasibility trial evaluating the use of an agent, metformin, in youth with MS, which has been funded by the Ontario Institute of Regenerative Medicine.
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论文共 418 篇作者统计合作学者相似作者
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Multiple sclerosis and related disorders (2024): 105916-105916
COMMUNICATIONS MEDICINEno. 1 (2024)
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2024): 105364-105364
Multiple sclerosis and related disorders (2024): 105758-105758
Eleonora A Grasso, Luke Bloy, Phillip Kaplan, Amit Bar-Or,E Ann Yeh, Douglas L Arnold,Sridar Narayanan,Ruth Ann Marrie,Giulia Fadda, Brenda L Banwell, Canadian Demyelinating Disease Network
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2024): 105599-105599
Multiple sclerosis and related disorders (2024): 105444-105444
Carmen Yea,Michelle Barton,Ari Bitnun,Shaun K. Morris,Tala El Tal,Rolando Ulloa-Gutierrez,Helena Brenes-Chacon,Adriana Yock-Corrales,Gabriela Ivankovich-Escoto,Alejandra Soriano-Fallas,Marcela Hernandez-de Mezerville,Peter Gill,Alireza Nateghian,Behzad Haghighi Aski,Ali Anari Manafi,Rachel Dwilow,Jared Bullard,Jesse Papenburg,Rosie Scuccimarri,Marie-Astrid Lefebvre,Suzette Cooke,Tammie Dewan,Lea Restivo,Alison Lopez,Manish Sadarangani,Ashley Roberts,Jacqueline Wong,Nicole Le Saux,Jennifer Bowes,Rupeena Purewal,Janell Lautermilch,Cheryl Foo,Joanna Merckx,Joan Robinson,E. Ann Yeh
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCESno. 1 (2024): 40-49
The Lancet Child & adolescent healthno. 5 (2024): 313-315
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#Papers: 418
#Citation: 5874
H-Index: 39
G-Index: 69
Sociability: 8
Diversity: 0
Activity: 4
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