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职业迁徙
个人简介
Research Interests
My group is interested in the identification of functional variation in two major contexts: the adaptive immune system and genetic association studies. In the adaptive immune system we have developed tools to extract and sequence millions of somatically rearranged t-cell receptor sequences from a specimen, and we are pursuing the application of this technology in several arenas, including the process of breaking tolerance in autoimmune disease, the process of developing protective immunity after vaccination, and screening for common exposures by comparing public sequences between individuals.
Our other interests are largely in the arena of identifying putatively functional variation in the regions that are statistically associated with disease after GWAS studies. This includes interpretation and extension of genome-wide association studies, and the identification of functional variation that is causally related to the statistical associations observed in GWAS.
In a related context, we have recently entered the field of exome sequencing, where we are assessing the enrichment of individuals from the extreme tails of phenotypic distributions for rare, putatively functional variants, in an effort to identify novel genes and pathways associated with phenotypes of interest.
研究兴趣
论文共 317 篇作者统计合作学者相似作者
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Zhe Zhong, Manuel Quiñones-Pérez, Zhonghao Dai,Valeria M Juarez,Eshant Bhatia,Christopher R Carlson,Shivem B Shah, Anjali Patel,Zhou Fang,Thomas Hu,Mayar Allam,Sakeenah L Hicks,Mansi Gupta,Sneh Lata Gupta, Ethan Weeks, Stephanie D Vagelos, Alejandro Molina, Adriana Mulero-Russe,Ana Mora-Boza, Devyani J Joshi,Rafick P Sekaly,Todd Sulchek,Steven L Goudy,Jens Wrammert,Krishnendu Roy,Jeremy M Boss,Ahmet F Coskun,Christopher D Scharer,Andrés J García,Jean L Koff,Ankur Singh
Nature materials (2024)
Jessica I. Lundin,Ulrike Peters,Yao Hu,Farah Ammous,Christy L. Avery,Emelia J. Benjamin,Joshua C. Bis,Jennifer A. Brody,Chris Carlson,Mary Cushman,Chris Gignoux,Xiuqing Guo,Jeff Haessler,Chris Haiman,Roby Joehanes,Silva Kasela,Eimear Kenny, Tuuli Lapalainien,Daniel Levy,Chunyu Liu,Yongmei Liu,Ruth J. F. Loos,Ake Lu,Tara Matise,Kari E. North,Sungshim L. Park,Scott M. Ratliff,Alex Reiner,Stephen S. Rich,Jerome I. Rotter,Jennifer A. Smith,Nona Sotoodehnia,Russell Tracy,David Van den Berg,Huichun Xu,Ting Ye,Wei Zhao,Laura M. Raffield,Charles Kooperberg
Epigeneticsno. 1 (2024)
Xinruo Zhang,Jennifer A Brody,Mariaelisa Graff,Heather M Highland,Nathalie Chami,Hanfei Xu,Zhe Wang,Kendra Ferrier,Geetha Chittoor,Navya S Josyula,Xihao Li,Zilin Li,Matthew A Allison,Diane M Becker,Lawrence F Bielak,Joshua C Bis,Meher Preethi Boorgula,Donald W Bowden,Jai G Broome,Erin J Buth,Christopher S Carlson,Kyong-Mi Chang,Sameer Chavan,Yen-Feng Chiu,Lee-Ming Chuang,Matthew P Conomos,Dawn L DeMeo,Margaret Du,Ravindranath Duggirala,Celeste Eng,Alison E Fohner,Barry I Freedman,Melanie E Garrett,Xiuqing Guo,Chris Haiman,Benjamin D Heavner,Bertha Hidalgo,James E Hixson,Yuk-Lam Ho,Brian D Hobbs,Donglei Hu,Qin Hui,Chii-Min Hwu,Rebecca D Jackson,Deepti Jain,Rita R Kalyani,Sharon L R Kardia,Tanika N Kelly,Ethan M Lange,Michael LeNoir,Changwei Li,Loic Le Marchand,Merry-Lynn N McDonald,Caitlin P McHugh,Alanna C Morrison,Take Naseri, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium,Jeffrey O'Connell,Christopher J O'Donnell,Nicholette D Palmer,James S Pankow,James A Perry,Ulrike Peters,Michael H Preuss,D C Rao,Elizabeth A Regan,Sefuiva M Reupena,Dan M Roden,Jose Rodriguez-Santana,Colleen M Sitlani,Jennifer A Smith,Hemant K Tiwari,Ramachandran S Vasan,Zeyuan Wang,Daniel E Weeks,Jennifer Wessel,Kerri L Wiggins,Lynne R Wilkens,Peter W F Wilson,Lisa R Yanek,Zachary T Yoneda,Wei Zhao,Sebastian Zöllner,Donna K Arnett,Allison E Ashley-Koch,Kathleen C Barnes,John Blangero,Eric Boerwinkle,Esteban G Burchard,April P Carson,Daniel I Chasman,Yii-Der Ida Chen,Joanne E Curran,Myriam Fornage,Victor R Gordeuk,Jiang He,Susan R Heckbert,Lifang Hou,Marguerite R Irvin,Charles Kooperberg,Ryan L Minster,Braxton D Mitchell,Mehdi Nouraie,Bruce M Psaty,Laura M Raffield,Alexander P Reiner,Stephen S Rich,Jerome I Rotter,M Benjamin Shoemaker,Nicholas L Smith,Kent D Taylor,Marilyn J Telen,Scott T Weiss,Yingze Zhang,Nancy Heard-Costa,Yan V Sun,Xihong Lin,L Adrienne Cupples,Leslie A Lange,Ching-Ti Liu,Ruth J F Loos,Kari E North,Anne E Justice
Elizabeth D. Kantor,Carolyn M. Hutter,Jessica Minnier,Sonja I. Berndt,Hermann Brenner,Bette J. Caan,Peter T. Campbell,Christopher S. Carlson,Graham Casey,Andrew T. Chan,Jenny Chang-Claude,Stephen J. Chanock,Michelle Cotterchio,Mengmeng Du,David Duggan,Charles S. Fuchs,Edward L. Giovannucci,Jian Gong,Tabitha A. Harrison,Richard B. Hayes,Brian E. Henderson,Michael Hoffmeister,John L. Hopper,Mark A. Jenkins,Shuo Jiao,Laurence N. Kolonel,Loic Le Marchand,Mathieu Lemire,Jing Ma,Polly A. Newcomb,Heather M. Ochs-Balcom,Bethann M. Pflugeisen,John D. Potter,Anja Rudolph,Robert E. Schoen,Daniela Seminara,Martha L. Slattery,Deanna L. Stelling,Fridtjof Thomas,Mark Thornquist,Cornelia M. Ulrich,Greg S. Warnick,Brent W. Zanke,Ulrike Peters,Li Hsu,Emily White
crossref(2023)
openalex(2023)
crossref(2023)
crossref(2023)
Elizabeth D. Kantor,Carolyn M. Hutter,Jessica Minnier,Sonja I. Berndt,Hermann Brenner,Bette J. Caan,Peter T. Campbell,Christopher S. Carlson,Graham Casey,Andrew T. Chan,Jenny Chang-Claude,Stephen J. Chanock,Michelle Cotterchio,Mengmeng Du,David Duggan,Charles S. Fuchs,Edward L. Giovannucci,Jian Gong,Tabitha A. Harrison,Richard B. Hayes,Brian E. Henderson,Michael Hoffmeister,John L. Hopper,Mark A. Jenkins,Shuo Jiao,Laurence N. Kolonel,Loic Le Marchand,Mathieu Lemire,Jing Ma,Polly A. Newcomb,Heather M. Ochs-Balcom,Bethann M. Pflugeisen,John D. Potter,Anja Rudolph,Robert E. Schoen,Daniela Seminara,Martha L. Slattery,Deanna L. Stelling,Fridtjof Thomas,Mark Thornquist,Cornelia M. Ulrich,Greg S. Warnick,Brent W. Zanke,Ulrike Peters,Li Hsu,Emily White
crossref(2023)
crossref(2023)
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作者统计
#Papers: 318
#Citation: 25067
H-Index: 67
G-Index: 156
Sociability: 8
Diversity: 4
Activity: 43
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