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职业迁徙
个人简介
Dr. Liu has a long-term interest in understanding of molecular basis of psychiatric diseases. His laboratory participated in one of the bipolar genetics research consortiums and discovered the rare copy number variant (CNV) burden in early-onset bipolar disorder. His lab is one of the leading research groups on genome-wide study of postmortem brain gene expression and DNA methylation, pioneered in study of gene expression regulatory network in human brain. He established the methylation quantitative trait loci (mQTLs) in human brain, indicating that DNA methylation of some sequences could be highly regulated by genetic variants. His lab currently focuses more on understanding genomic and epigenomic mechanisms in human brains for psychiatric disorders. His research has been supported by NIMH, NARSAD, and Brain Research Foundation. He has published more than 100 peer-reviewed papers and several book chapters, and been cited for more than 7,000 times, with H-index of 37. He has served as reviewer for dozens of journals and foundations including NIH. Dr. Liu’s major research focuses on using a comprehensive approach that is composed of genetics, bioinformatics, genomics, cellular and animal models to identify the molecular mechanisms of major psychiatric diseases, particularly bipolar disorder and schizophrenia. Constructing multidimensional regulatory network in human brains, and relating that to etiology and pathology of mental illness is the major mission of this lab.
Current major NIH-funded project is the psychENCODE project, investigating multi-dimensional biological features, networks in brains of bipolar disorder, schizophrenia and normal.
Current major NIH-funded project is the psychENCODE project, investigating multi-dimensional biological features, networks in brains of bipolar disorder, schizophrenia and normal.
研究兴趣
论文共 757 篇作者统计合作学者相似作者
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Maria Teresa Ferretti,Huitong Ding,Rhoda Au,Chunyu Liu,Sherral Devine,Sanford Auerbach,Jesse Mez, Ashita Gurnani,Yulin Liu, Antonella Santuccione,Ting Fang Alvin Ang
ALZHEIMERS & DEMENTIAno. 2 (2024): 1112-1122
Yu Chen,Sihan Liu,Zongyao Ren,Feiran Wang,Yi Jiang,Rujia Dai,Fangyuan Duan,Cong Han,Zhilin Ning,Yan Xia, Miao Li, Kai Yuan,
medRxiv : the preprint server for health sciences (2024)
Jiun- Lai,Ting-Hao Kuo, Kuan-Jung Huang,Laura Min Xuan Chai,Mei-Hsuan Lee,Chun-Yu Liu,Yi-Fang Tsai,Chi-Cheng Huang,Ling-Ming Tseng,Cheng-Chih Hsu,Ta-Chung Chao
ONCOLOGISTno. 4 (2024): e455-e466
THORACIC CANCERno. 4 (2024): 339-346
Rujia Dai, Ming Zhang, Tianyao Chu,Richard Kopp,Chunling Zhang,Kefu Liu,Yue Wang,Xusheng Wang,Chao Chen,Chunyu Liu
crossref(2024)
Rujia Dai, Ming Zhang, Tianyao Chu,Richard Kopp,Chunling Zhang,Kefu Liu,Yue Wang,Xusheng Wang,Chao Chen,Chunyu Liu
bioRxiv : the preprint server for biology (2024)
Helena Bui,Amena Keshawarz, Mengyao Wang, Mikyeong Lee,Scott M Ratliff,Lisha Lin,Kira S Birditt,Jessica D Faul,Annette Peters,Christian Gieger,Thomas Delerue,Sharon L R Kardia,
medRxiv : the preprint server for health sciences (2024)
The Cochrane database of systematic reviewsno. 5 (2024): CD015213-CD015213
Yi-Fang Tsai,Chi-Cheng Huang,Chih-Yi Hsu,Chin-Jung Feng, Yen-Shu Lin, Ta-Chung Chao, Jiun- Lai,Pei-Ju Lien,Chun-Yu Liu,Jen-Hwey Chiu,Ling-Ming Tseng
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 2 (2024): 1318
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