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个人简介
My expertise is in the field of respiratory viruses, in particular influenza viruses. My studies aim to understand the molecular and cellular basis of the pathogenesis, host range restrictions and transmissibility of influenza viruses. The approach includes the generation of recombinant viruses with defined mutations. This strategy has contributed to the production of novel influenza pandemic vaccines. In principle, the work employs the most appropriate virus strains and relevant cell or animal models. Primary influenza clinical strains are obtained through a long-standing collaboration with the Health Protection Agency, and viruses are studied on primary human airway cells and in ferrets. Translational aspects include analysing mode of action and resistance mechanisms of antiviral compounds, and characterization of novel cell substrates and attenuated virus backbones for influenza vaccines. The laboratory is funded by MRC, BBSRC, the Wellcome Trust and commercial bodies.
研究兴趣
论文共 327 篇作者统计合作学者相似作者
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Maximillian N. J. Woodall,Ana-Maria Cujba,Kaylee B. Worlock,Katie-Marie Case,Tereza Masonou,Masahiro Yoshida,Krzysztof Polanski,Ni Huang,Rik G. H. Lindeboom,Lira Mamanova,Liam Bolt,Laura Richardson,Batuhan Cakir,Samuel Ellis,Machaela Palor,Thomas Burgoyne,Andreia Pinto,Dale Moulding,Timothy D. McHugh,Aarash Saleh,Eliz Kilich,Puja Mehta,Chris O'Callaghan,Jie Zhou,Wendy Barclay,Paolo DeCoppi,Colin R. Butler,Mario Cortina-Borja,Heloise Vinette,Sunando Roy,Judith Breuer,Rachel C. Chambers,Wendy E. Heywood,Kevin Mills,Robert E. Hynds,Sarah A. Teichmann,Kerstin B. Meyer,Marko Z. Nikolic,Claire M. Smith
Nature Communicationsno. 1 (2024)
Jiayun Yang,Mehnaz Qureshi, Bhaktavatsala Reddy Kolli,Thomas P Peacock,Jean-Remy Sadeyen, Toby Carter,Samuel Richardson,Rebecca Daines,Wendy S Barclay,Ian H Brown,Munir Iqbal
biorxiv(2024)
Sarah Hulin-Curtis, James K. Geary,Bruce J. Maclachlan, Danny M. Altmann,Laury Baillon,David K. Cole,Alex Greenshields-Watson,Sophie J. Hesketh,Ian R. Humphreys,Ian M. Jones,Sarah N. Lauder,Georgina H. Mason,Kathryn Smart,D. Oliver Scourfield,Jake Scott,Ksenia Sukhova,Richard J. Stanton,Aaron Wall,Pierre J. Rizkallah,Wendy S. Barclay,Awen Gallimore,Andrew Godkin
Cell Reportsno. 6 (2024): 114259-114259
Michael A Crone,Seran Hakki,Joe Fenn,Jie Zhou,Carolina Rosadas de Oliveira,Kieran J Madon,Aleksandra Koycheva,Anjna Badhan,Jakob Jonnerby,Sean Nevin,Emily Conibear,Romain Derelle,Robert Varro, Constanta Luca,Shazaad Ahmad,Maria Zambon,Wendy S Barclay,Jake Dunning,Paul S Freemont,Graham P Taylor,Ajit Lalvani
Joanna Waldock,Rebecca J Cox,Christopher Chiu,Kanta Subbarao, Adrian Wildfire,Wendy Barclay, Puck B van Kasteren,John McCauley,Colin A Russell,Derek Smith,Ryan S Thwaites,John S Tregoning,Othmar G Engelhardt
Influenza and other respiratory virusesno. 11 (2024): e70014-e70014
The EMBO journalno. 24 (2024): 6469-6495
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作者统计
#Papers: 328
#Citation: 15676
H-Index: 63
G-Index: 119
Sociability: 8
Diversity: 3
Activity: 370
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