R. Scott Struthers - Department of Endocrinology, Neurocrine Biosciences, Inc.

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论文共 13 篇作者统计合作学者相似作者

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Acromegaly Disease Control Maintained after Switching from Injected Somatostatin Receptor Ligands to Oral Paltusotine

Monica R. Gadelha,Alessandra Casagrande,Christian J. Strasburger,Martin Bidlingmaier,Peter J. Snyder,Mirtha A. Guitelman,Cesar L. Boguszewski,Michael Buchfelder,Ilan Shimon,Gerald Raverot,Miklos Toth,Emese Mezosi,Mirjana Doknic, Xiaolin Fan,David Clemmons,Peter J. Trainer,R. Scott Struthers,Alan Krasner,Beverly M. K. Biller

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2024)

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Discovery of CRN04894: A Novel Potent Selective MC2R Antagonist

Sun Hee Kim,Sangdon Han,Jian Zhao,Shimiao Wang,Ana Karin Kusnetzow,Greg Reinhart,Melissa A. Fowler,Stacy Markison,Michael Johns,Rosa Luo,R. Scott Struthers,Yunfei Zhu,Stephen F. Betz

ACS Medicinal Chemistry Lettersno. 4 (2024): 478-485

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8404 Use of the Acromegaly Symptom Diary (ASD) in a Phase 3, Placebo-Controlled Study of Once-Daily, Oral Paltusotine in Patients with Acromegaly Switched from Injected Octreotide or Lanreotide

Monica Roberto Gadelha,Alessandra Casagrande,Christian Joseph Strasburger, Martin Bidlingmaier,Peter J Snyder,Mirtha Adriana Guitelman, Cesar Luiz Boguszewski,Michael Buchfelder,Ilan Shimon,Gerald Raverot,Miklos Toth,Emese Mezosi,Mirjana Doknic, Xiaolin Fan,David Clemmons, Michael Keeley,Peter James Trainer,R Scott Struthers,Alan Krasner,Beverly M K Biller

Journal of the Endocrine Societyno. Supplement_1 (2024)

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SAT628 Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Oral Paltusotine, A Non-peptide, Selective Somatostatin Receptor Subtype 2 Agonist

Rosa Luo,Alessandra Casagrande, Sonic Oun, Yang Wang,R Scott Struthers,Alan Krasner

Journal of the Endocrine Societyno. Supplement_1 (2023)

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Potent and Orally Bioavailable Zwitterion GnRH Antagonists with Low CYP3A4 Inhibitory Activity

Chen,Yongsheng Chen,Joseph Pontillo,Zhiqiang Guo,Charles Q. Huang,Dongpei Wu,Ajay Madan,Takung Chen,Jenny Wen,Qiu Xie,Fabio C. Tucci,Martin Rowbottom,Yun-Fei Zhu,Warren Wade,John Saunders,Haig Bozigian,R. Scott Struthers

Bioorganic & medicinal chemistry letters（2008）

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5-Aryluracils As Potent Gnrh Antagonists - Characterization of Atropisomers

Liren Zhao,Zhiqiang Guo,Yongsheng Chen,Tao Hu,Dongpei Wu,Yun-Fei Zhu,Martin Rowbottom, Timothy D. Gross,Fabio C. Tucci,R. Scott Struthers,Qiu Xie, Chen

Bioorganic & medicinal chemistry letters（2008）

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Trapping of a Nonpeptide Ligand by the Extracellular Domains of the Gonadotropin-Releasing Hormone Receptor Results in Insurmountable Antagonism

Trudy A. Kohout,Qiu Xie,Shelby Reijmers,Kenneth J. Finn,Zhiqiang Guo,Yun-Fei Zhu,R. Scott Struthers

Molecular pharmacology（2007）

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Synthesis and Structure—Activity Relationships of (r)‐1‐alkyl‐3‐[2‐(2‐amino)phenethyl]‐5‐(2‐fluorophenyl)‐6‐methyluracils As Human GnRH Receptor Antagonists

Martin W. Rowbottom,Fábio C. Tucci,Yunfei Zhu,Zhiqiang Guo, Timothy D. Gross,Greg J. Reinhart,Qui Xie,R. Scott Struthers,John Saunders, Chen

Chem Inform（2004）

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Synthesis and Structure—Activity Relationships of 1‐arylmethyl‐3‐(2‐aminopropyl)‐5‐aryl‐6‐methyluracils As Potent GnRH Receptor Antagonists

Zhiqiang Guo,Yun‐Fei Zhu, Fabio C. Tucci,Yinghong Gao,R. Scott Struthers,John Saunders,Timothy D. Gross,Qiu Xie,Greg J. Reinhart, Chen

ChemInform（2003）

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