Hafey Michael J - Dept Pharmacokinet Pharmacodynam & Drug Metab PPD, Merck & Co Inc

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论文共 28 篇作者统计合作学者相似作者

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SAT-412 Low Risk of Drug-Drug Interactions for Ruzasvir Based Upon in Vitro Metabolism and Transporter Interaction Studies

Alex Vo,Jocelyn Yabut,Michael Hafey, Hui Wan, Nancy Agrawal,Jean-Pierre Sommadossi

JOURNAL OF HEPATOLOGY (2024): S753-S753

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Physiologically-based Modeling of Cholate Disposition in Beagle Dog with and Without Treatment of the Liver Transporter Inhibitor Simeprevir

Shu-Wen Teng,Michael Hafey,Jeanine Ballard,Xinjie Lin,Changhong Yun,Vijay More,Robert Houle,Ravi Katwaru,Ann Thomas,Grace Chan, Kim Michel,Yutai Li,Kara Pearson,Christopher Gibson

Computational Toxicology (2022)

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Transporters and Toxicity: Insights from the International Transporter Consortium Workshop 4

Michael J. Hafey,Lauren M. Aleksunes,Christy C. Bridges,Kenneth R. Brouwer,Huan-Chieh Chien,Elaine M. Leslie,Shuiying Hu, Yang Li, Jinshan Shen,Alex Sparreboom,Jason Sprowl,Donald Tweedie,Yurong Lai

CLINICAL PHARMACOLOGY & THERAPEUTICSno. 3 (2022): 527-539

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Islatravir is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions Via Major Drug-Metabolizing Enzymes or Transporters

Kelly Bleasby,Robert Houle,Michael Hafey,Meihong Lin, Jingjing Guo,Bing Lu,Rosa I. Sanchez,Kerry L. Fillgrove

Virusesno. 8 (2021): 1566-1566

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P84 - A Platform for Evaluating in Vivo OATP1B Inhibition Risk in Cynomolgus Monkeys and Translation to Human

Daniel Tatosian,Ying Li, Kimberly Michel,Christine Bowman,Lauren Zepp,Michael Hafey,Xiaoyan Chu,Rena Zhang,Ken Anderson,Tjerk Bueters,Maria Trujillo,Raymond Evers

DRUG METABOLISM AND PHARMACOKINETICS（2020）

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A Two-Tiered in Vitro Approach to De-Risk Drug Candidates for Potential Bile Salt Export Pump Inhibition Liabilities in Drug Discovery

Michael J. Hafey,Robert Houle,Keith Q. Tanis,Ian Knemeyer,Jackie Shang,Qing Chen,Andreas Baudy,James Monroe,Frank D. Sistare,Raymond Evers

Drug Metabolism and Disposition（2020）

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Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity

Yutai Li,Raymond Evers,Michael J. Hafey,Kyeongmi Cheon,Hong Duong,Donna Lynch,Lisa LaFranco-Scheuch,Stephen Pacchione,Alex M. Tamburino, Keith Q. Tanis, Kristin Geddes, Daniel Holder, Nanyan Rena Zhang, Wen Kang,Raymond J. Gonzalez,Alema Galijatovic-Idrizbegovic,Kara M. Pearson,Jose A. Lebron,Warren E. Glaab,Frank D. Sistare

Toxicological Sciencesno. 1 (2019): 180-198

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Augmenting Decision Making in Early Discovery – Efforts to Derisk Bsep Inhibition Potential Utilizing in Silico Modeling

Elizabeth Joshi,Michael Hafey,Robert Houle,Prabha Karnachi

Drug Metabolism and Pharmacokinetics（2018）

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Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

J. Gerry Kenna,Kunal S. Taskar,Christina Battista,David L. Bourdet,Kim L.R. Brouwer,Kenneth R. Brouwer,David Dai,Christoph Funk,Michael J. Hafey,Yurong Lai,Jonathan Maher,Y. Anne Pak,Jenny M. Pedersen,Joseph W. Polli,A. David Rodrigues,Paul B. Watkins,Kyunghee Yang,Robert W. Yucha

CLINICAL PHARMACOLOGY & THERAPEUTICSno. 5.0 (2018): 916-932

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