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个人简介
Our work focuses on immunology in the lung and its influence on acute lower respiratory tract infections. Our research is illuminating the regulation and function of innate and adaptive immune cells and signals in the lung, and how variations in these parameters determine pneumonia susceptibility and outcome. Lung defense consists of immune resistance (the ability to eliminate microbes) and tissue resilience (the ability to prevent or withstand injurious stimuli from infection and inflammation). Both activities are accomplished by the coordinated activities of diverse cell types within the lung, involving some that are constitutively present (including diverse types of epithelial cells, macrophages, lymphocytes, and more) as well as others newly recruited to the infected tissue (including neutrophils plus additional myeloid or lymphoid cells). Effective and productive communication amongst these cells can efficiently destroy microbes without damaging the lung, maintaining respiratory health. Dysregulation of these pathways instead promotes infection (e.g., pneumonia), injury (e.g., the acute respiratory distress syndrome), and other pulmonary diseases. Elucidating factors that differentiate lung infection resistance and susceptibility will enable new approaches to preventing and treating pneumonia.
研究兴趣
论文共 301 篇作者统计合作学者相似作者
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F.T. Korkmaz, T. Horace, R. Wallace, M. Perez Vazquez,M. Ozkan,J. Mehta,T. Sawamura, M.R. Jones,K. Traber,J.P. Mizgerd,L.J. Quinton
C14 HARMONY IN HEALING IMMUNE CELL CHOREGRAPHY OF LUNG INJURY AND REPAIR (2024)
Vijay Raaj Ravi,Filiz T. Korkmaz,Carolina Lyon De Ana, Lu,Feng-Zhi Shao,Christine V. Odom,Kimberly A. Barker,Aditya Ramanujan, Emma N. Niszczak,Wesley N. Goltry,Ian M.C. Martin, Catherine T. Ha,Lee J. Quinton,Matthew R. Jones,Alan Fine,Joshua D. Welch,Felicia Chen,Anna C. Belkina,Joseph P. Mizgerd,Anukul T. Shenoy
biorxiv(2024)
Sara C Auld,Ajay Sheshadri, Jennifer Alexander-Brett,Yael Aschner,Amy K Barczak,Maria C Basil,Keira A Cohen,Charles Dela Cruz,Claire McGroder,Marcos I Restrepo,Karen M Ridge,Lynn M Schnapp,Katrina Traber,Richard G Wunderink,David Zhang,Assem Ziady,Engi F Attia, Jane Carter,James D Chalmers,Kristina Crothers,Charles Feldman,Barbara E Jones,Naftali Kaminski,Joseph Keane,David Lewinsohn,Mark Metersky,Joseph P Mizgerd,Alison Morris,Julio Ramirez,Amali E Samarasinghe,Bashar S Staitieh,Cari Stek,Jie Sun,Scott E Evans
Annals of the American Thoracic Societyno. 9 (2024): 1219-1237
Alexandra B. Ysasi,Anna E. Engler,Pushpinder Singh Bawa,Feiya Wang, Regan D. Conrad,Anthony K. Yeung,Jason R. Rock, Jennifer Beane-Ebel,Sarah A. Mazzilli,Ruth A. Franklin,Joseph P. Mizgerd,George J. Murphy
iScienceno. 7 (2024): 110169-110169
C67 SCIENCE AND BEDSIDE BACTERIAL PNEUMONIA (2024)
N. Sanders,A.T. Shenoy,N.S. Etesami, K. Kontodimas, C. Okolo, D.J. Kenney,D. Bean, J. Lederer,M. Sagar, F. Douam,M. Saeed,J.P. Mizgerd
B33. COVID-19, LUNG INJURY, AND SEPSIS (2024)
The Journal of clinical investigationno. 19 (2024)
PLoS ONEno. 7 (2024): e0296139-e0296139
Neelou S. Etesami,Kimberly A. Barker,Anukul T. Shenoy,Carolina Lyon De Ana,Emad I. Arafa,Gabrielle N. Grifno,Adeline M. Matschulat, Michael E. Vannini,Riley M. F. Pihl, Michael P. Breen,Alicia M. Soucy,Wesley N. Goltry, Catherine T. Ha, Hanae Betsuyaku,Jeffrey L. Browning,Xaralabos Varelas,Katrina E. Traber,Matthew R. Jones,Lee J. Quinton,Paul J. Maglione,Hadi T. Nia,Anna C. Belkina,Joseph P. Mizgerd
FRONTIERS IN IMMUNOLOGY (2024)
Jie Yin, Kevin M. Hayes, Mei-Sing Ong,Joseph P. Mizgerd,Charlotte Cunningham-Rundles, Isabel Dominguez,Sara Barmettler, Jocelyn R. Farmer, Paul J. Maglione
The Journal of Allergy and Clinical Immunology In Practice (2024)
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作者统计
#Papers: 302
#Citation: 9452
H-Index: 51
G-Index: 95
Sociability: 7
Diversity: 3
Activity: 62
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