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Dr. Barbara Jones seeks to understand how the brain generates states of waking and sleep. She studies the chemical neurotransmitters, anatomical projections and physiology of the specific neurons that stimulate and maintain a waking state, as well as those neurons that reciprocally arrest waking and promote sleep. In this process, different neural systems interact to generate three distinct states: waking, slow wave sleep (SWS) and paradoxical sleep (PS, or rapid eye movement sleep, REM, when dreaming occurs). To study these neural systems, she uses immunohistochemical and neuroanatomical techniques combined with neurophysiological recording. She is examining the way that cholinergic neurons in the brain stem and basal forebrain stimulate cortical activation with theta and gamma electroencephalographic (EEG) activity during waking and PS and participate in processes of attention and memory. Due in part to loss of cholinergic neurons, these processes are compromised in neurological diseases such as Alzheimer's Disease.
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论文共 352 篇作者统计合作学者相似作者
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Studies in health technology and informatics (2024): 1444-1445
Khanh N C Duong,Lan M Le,Sajesh K Veettil, Pantakarn Saidoung,Warintorn Wannaadisai,Richard E Nelson, Mike Friedrichs,Barbara E Jones,Andrew T Pavia,Makoto M Jones,Matthew H Samore,Nathorn Chaiyakunapruk
Frontiers in public health (2023): 1206988
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JAMA network openno. 5 (2023): e2315829-e2315829
JAMA network openno. 5 (2023): e2314185-e2314185
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Open forum infectious diseasesno. 7 (2023)
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Jason R Carr,Barbara E Jones,Dave S Collingridge,Brandon J Webb,Caroline Vines, Blake Zobell,Todd L Allen,Rajendu Srivastava,Jenna Rubin,Nathan C Dean
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