Ferran Fece de la Cruz - Massachusetts General Hospital

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Abstract LB449: Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway

Ferran Fece de la Cruz,Andreas Varkaris,Elizabeth E. Martin, Bryanna L. Norden,Nicholas Chevalier,Allison M. Kehlmann,Ignaty Leshchiner,Haley Barnes,Sara Ehnstrom,Parasvi Patel,Janice S. Kim,Haley Ellis,Ioannis Sanidas, Kayao T. Lau,Aditya Bardia,Laura M. Spring,Steven J. Isakoff,Jochen K. Lennerz,Gad Getz,Ryan B. Corcoran,Dejan Juric

Cancer Researchno. 7_Supplement (2024)

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Supplementary Figure S1 from Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma

Qibiao Wu,Haley Ellis,Giulia Siravegna,Alexa G. Michel,Bryanna L. Norden,Ferran Fece de la Cruz, Eranga Roshan Balasooriya,Yuanli Zhen,Vanessa S. Silveira, Jianwe Che,Ryan B. Corcoran,Nabeel Bardeesy

crossref（2024）

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Supplementary Figures S1-S7 from Sotorasib is a Pan-RASG12C Inhibitor Capable of Driving Clinical Response in nrasg12c Cancers

Douglas A. Rubinson,Noritaka Tanaka,Ferran Fece de la Cruz,Kevin S. Kapner,Michael H. Rosenthal, Bryanna L. Norden,Haley Barnes,Sara Ehnstrom,Alvin A. Morales-Giron,Lauren K. Brais,Christopher T. Lemke, Andrew J. Aguirre,Ryan B. Corcoran

crossref（2024）

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Sotorasib is a Pan-RASG12C Inhibitor Capable of Driving Clinical Response in NRASG12C Cancers

Douglas A. Rubinson,Noritaka Tanaka,Ferran Fece de la Cruz,Kevin S. Kapner,Michael H. Rosenthal,Bryanna L. Norden,Haley Barnes,Sara Ehnstrom,Alvin A. Morales-Giron,Lauren K. Brais,Christopher T. Lemke,Andrew J. Aguirre,Ryan B. Corcoran

CANCER DISCOVERYno. 5 (2024): 727-736

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Supplementary Tables S1 to S5 from Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations

Andreas Varkaris,Ferran Fece de la Cruz,Elizabeth E. Martin,Bryanna L. Norden,Nicholas Chevalier,Allison M. Kehlmann,Ignaty Leshchiner,Haley Barnes,Sara Ehnstrom, Anastasia-Maria Stavridi, Xin Yuan,Janice S. Kim,Haley Ellis,Alkistis Papatheodoridi, Hakan Gunaydin,Brian P. Danysh,Laxmi Parida,Ioannis Sanidas, Yongli Ji, Kayao Lau, Gerburg M. Wulf,Aditya Bardia,Laura M. Spring,Steven J. Isakoff,Jochen K. Lennerz, Kathryn Del Vecchio,Levi Pierce,Ermira Pazolli, Gad Getz,Ryan B. Corcoran, Dejan Juric

crossref（2024）

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Supplementary Figures S1 to S11 from Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary pik3ca Mutations

Andreas Varkaris,Ferran Fece de la Cruz,Elizabeth E. Martin,Bryanna L. Norden,Nicholas Chevalier,Allison M. Kehlmann,Ignaty Leshchiner,Haley Barnes,Sara Ehnstrom, Anastasia-Maria Stavridi, Xin Yuan,Janice S. Kim,Haley Ellis,Alkistis Papatheodoridi, Hakan Günaydın,Brian P. Danysh,Laxmi Parida,Ioannis Sanidas, Yongli Ji, Kelvin Lau, Gerburg M. Wulf,Aditya Bardia,Laura M. Spring,Steven J. Isakoff,Jochen K. Lennerz, Kathryn Del Vecchio,Levi Pierce,Ermira Pazolli, Gad Getz,Ryan B. Corcoran, Dejan Juric

openalex（2024）

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Abstract GS03-10: Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations

Cancer Researchno. 9_Supplement (2024): GS03-10

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Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations

Andreas Varkaris,Ferran Fece de la Cruz,Elizabeth E. Martin,Bryanna L. Norden,Nicholas Chevalier, Allison M. Kehlmann,Ignaty Leshchiner, Haley Barnes, Sara Ehnstrom, Anastasia-Maria Stavridi,Xin Yuan,Janice S. Kim, Haley Ellis,Alkistis Papatheodoridi,Hakan Gunaydin,Brian P. Danysh,Laxmi Parida,Ioannis Sanidas,Yongli Ji, Kayao Lau,Gerburg M. Wulf,Aditya Bardia,Laura M. Spring,Steven J. Isakoff,Jochen K. Lennerz, Kathryn Del Vecchio,Levi Pierce,Ermira Pazolli,Gad Getz,Ryan B. Corcoran,Dejan Juric

CANCER DISCOVERY（2024）

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Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma

Qibiao Wu,Haley Ellis,Giulia Siravegna,Alexa G. Michel,Bryanna L. Norden,Ferran Fece de la Cruz, Eranga Roshan Balasooriya,Yuanli Zhen,Vanessa S. Silveira, Jianwe Che,Ryan B. Corcoran,Nabeel Bardeesy

CLINICAL CANCER RESEARCHno. 1 (2024): 198-208

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Abstract LB366: KRASG12C inhibition enhances immunogenicity in KRASG12C-mutant colorectal cancer

Parasvi S. Patel, Jun Tian,Ferran Fece de la Cruz, Jacquelyn Curtis, Apekshya Panda,Tomonori Oka,Shadmehr Demehri,Moshe Sade-Feldman, Scott Koptez,Ryan B. Corcoran

Cancer Researchno. 7_Supplement (2024)

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