Dr. Hein’s research program incorporates precision environmental health and precision medicine. This includes research in personalized medicine and individual susceptibility to environmental diseases. Research in molecular epidemiology identifies individuals genetically susceptible to the development of cancer and other diseases from environmental and occupational chemicals to focus treatment and prevention public health strategies on those at greatest risk. Research in pharmacogenetics/genomics and personalized/precision medicine improves our understanding of the genetic causes for drug failure and/or drug toxicity in order to optimize clinical drug therapy for each individual patient. Research in functional genomics improves understanding of the mechanistic and clinical consequences of genetic variation in the biotransformation of environmental chemicals, carcinogens and drugs. The research program has been funded continuously since 1983 by grants and contracts from the National Institutes of Health and other federal and private foundations and industry. He has coauthored over 275 peer-reviewed journal articles and book chapters, 75 gene sequences, and over 700 abstracts with over 17,000 citations (h-index=67) in the scientific literature. He has presented 150 invited research seminars in Australia, Austria, Canada, China, Czech Republic, Egypt, France, Germany, Greece, Italy, Norway, Switzerland, the United Kingdom and across the USA.