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个人简介
The Hunter laboratory has several areas of research that center around understanding how the immune system deals with T. gondii. The first focuses on host pathogen interactions at the cellular level and how the parasite interacts with intracellular signaling pathways (NF-kB/JAK-STAT). In collaboration with the Roos laboratory, genetic approaches are being used to identify parasite factors that are involved in these events. This is part of work in progress which has used transgenic parasites to address fundamental questions about which cells are important in the initiation of adaptive immunity and the role of cross-presentation in the development of T cell responses. These latter studies compliment the work in the laboratory that has helped to define the cytokine networks that regulate the balance between protective and pathological immune responses and current studies focus on the IL-6 family of cytokines in these events. Lastly the laboratory is interested in better understanding the pathogenesis of toxoplasmic encephalitis (TE) in the immunocompromised patients who develop this disease. This work has also led the laboratory to try and apply what we have learned in TE to better understand the neuro-pathogenesis of African sleeping sickness.
研究兴趣
论文共 504 篇作者统计合作学者相似作者
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Amin Abedini,Jonathan Levinsohn,Konstantin A. Klotzer,Bernhard Dumoulin,Ziyuan Ma,Julia Frederick,Poonam Dhillon,Michael S. Balzer,Rojesh Shrestha,Hongbo Liu,Steven Vitale, Andi M. Bergeson,Kishor Devalaraja-Narashimha, Paola Grandi,Tanmoy Bhattacharyya, Erding Hu,Steven S. Pullen,Carine M. Boustany-Kari,Paolo Guarnieri,Anil Karihaloo,Daniel Traum,Hanying Yan,Kyle Coleman,Matthew Palmer,Lea Sarov-Blat,Lori Morton,Christopher A. Hunter,Klaus H. Kaestner,Mingyao Li,Katalin Susztak
NATURE GENETICS (2024)
M. Haley Licon, Christopher J. Giuliano, Alex W. Chan, Sundeep Chakladar, Julia N. Eberhard, Lindsey A. Shallberg, Sambamurthy Chandrasekaran, Benjamin S. Waldman, Anita A. Koshy,Christopher A. Hunter,Sebastian Lourido
NATURE MICROBIOLOGYno. 4 (2024): 1145-1145
Serena Omo-Lamai, Yufei Wang,Manthan N Patel,Eno-Obong Essien,Mengwen Shen, Aparajeeta Majumdar, Carolann Espy,Jichuan Wu,Breana Channer,Michael Tobin,Shruthi Murali,Tyler E Papp, Rhea Maheshwari, Liuqian Wang,Liam S Chase,Marco E Zamora,Mariah L Arral,Oscar A Marcos-Contreras,Jacob W Myerson,Christopher A Hunter,Andrew Tsourkas,Vladimir Muzykantov,Igor Brodsky,Sunny Shin,Kathryn A Whitehead,Peter Gaskill,Dennis Discher,Hamideh Parhiz,Jacob S Brenner
bioRxiv : the preprint server for biology (2024)
biorxiv(2024)
JOURNAL OF EXPERIMENTAL MEDICINEno. 7 (2024)
PLOS PATHOGENSno. 5 (2024)
crossref(2024)
Emily A Aunins,Anthony T Phan,Mohamad-Gabriel Alameh,Elisa Cruz-Morales,David A Christian, Molly E Bunkofske,Garima Dwivedi,Drew Weissman,Christopher Hunter
biorxiv(2024)
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#Papers: 505
#Citation: 41668
H-Index: 104
G-Index: 197
Sociability: 8
Diversity: 0
Activity: 2
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