Frank Rigo - Isis Pharmaceuticals;Isis Pharmaceuticals

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论文共 231 篇作者统计合作学者相似作者

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Targeting the Transferrin Receptor to Transport Antisense Oligonucleotides Across the Mammalian Blood-Brain Barrier

Scarlett J. Barker,Mai B. Thayer,Chaeyoung Kim,David Tatarakis,Matthew J. Simon, Rebekah Dial, Lizanne Nilewski,Robert C. Wells,Yinhan Zhou,Megan Afetian,Padma Akkapeddi,Alfred Chappell,Kylie S. Chew,Johann Chow, Allisa Clemens, Claire B. Discenza,Jason C. Dugas,Chrissa Dwyer,Timothy Earr,Connie Ha, Yvonne S. Ho,David Huynh, Edwin I. Lozano, Srini Jayaraman,Wanda Kwan,Cathal Mahon,Michelle Pizzo,Yaneth Robles-Colmenares,Elysia Roche, Laura Sanders, Alexander Stergioulis,Raymond Tong,Hai Tran,Joy Yu Zuchero,Anthony A. Estrada,Kapil Gadkar, Christopher M. M. Koth,Pascal E. Sanchez,Robert G. Thorne,Ryan J. Watts,Thomas Sandmann,Lesley A. Kane,Frank Rigo,Mark S. Dennis,Joseph W. Lewcock,Sarah L. Devos

SCIENCE TRANSLATIONAL MEDICINEno. 760 (2024)

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Reduction of RAD23A Extends Lifespan and Mitigates Pathology in TDP-43 Mice

Xueshui Guo, Ravindra Prajapati, Jiyeon Chun,Insuk Byun, Kamil K Gebis,Yi-Zhi Wang,Karen Ling,Casey Dalton, Jeff A Blair,Anahid Hamidianjahromi, Gemma Bachmann,Frank Rigo,Paymaan Jafar-Nejad,Jeffrey N Savas, Min Jae Lee,Jemeen Sreedharan,Robert G Kalb

bioRxiv the preprint server for biology (2024)

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Modeling Antisense Oligonucleotide Therapy in MECP2 Duplication Syndrome Human Ipsc-Derived Neurons Reveals Gene Expression Programs Responsive to MeCP2 Levels

Sameer S. Bajikar,Yehezkel Sztainberg,Alexander J. Trostle, Harini P. Tirumala,Ying-Wooi Wan, Caroline L. Harrop,Jesse D. Bengtsson,Claudia M. B. Carvalho,Davut Pehlivan,Bernhard Suter,Jeffrey L. Neul,Zhandong Liu,Paymaan Jafar-Nejad,Frank Rigo,Huda Y. Zoghbi

HUMAN MOLECULAR GENETICSno. 22 (2024): 1986-2001

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Employing Splice-Switching Oligonucleotides and AAVrh74.U7 Snrna to Target Insulin Receptor Splicing and Cancer Hallmarks in Osteosarcoma

Safiya Khurshid, Akila S. Venkataramany,Matias Montes, John F. Kipp, Ryan D. Roberts,Nicolas Wein,Frank Rigo, Pin-Yi Wang, Timothy P. Cripe,Dawn S. Chandler

Molecular Therapy Oncologypp.200908, (2024)

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Elevating Microrna Levels by Targeting Biogenesis with Steric-Blocking Antisense Oligonucleotides

Mallory A. Havens,Anthony J. Hinrich,Frank Rigo,Michelle L. Hastings

RNA (New York, NY)no. 12 (2024): 1543-1553

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Targeting Alternative Splicing of Fibronectin in Human Renal Proximal Tubule Epithelial Cells with Antisense Oligonucleotides to Reduce EDA+ Fibronectin Production and Block an Autocrine Loop That Drives Renal Fibrosis

Mysore Keshavmurthy Phanish,Felicia Heidebrecht,Michaela Jackson,Frank Rigo,Mark Edward Carl Dockrell

EXPERIMENTAL CELL RESEARCHno. 1 (2024)

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Safety, Tolerability, and Pharmacokinetics of Antisense Oligonucleotide BIIB078 in Adults with C9orf72-associated Amyotrophic Lateral Sclerosis: a Phase 1, Randomised, Double Blinded, Placebo-Controlled, Multiple Ascending Dose Study

Leonard H. van den Berg,Jeffrey D. Rothstein,Pamela J. Shaw,Suma Babu,Michael Benatar,Robert C. Bucelli,Angela Genge,Jonathan D. Glass,Orla Hardiman,Vincenzo Libri, Theodore Mobach,Bjoern Oskarsson,Gary L. Pattee,John Ravits,Christopher E. Shaw,Markus Weber,Lorne Zinman,Paymaan Jafar-nejad,Frank Rigo, Luan Lin,Toby A. Ferguson, Anthony L. Gotter,Danielle Graham,Michael Monine, Jennifer Inra,Susie Sinks,Satish Eraly, Steve Garafalo,Stephanie Fradette

LANCET NEUROLOGYno. 9 (2024): 901-912

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Reduction of Kcnt1 is Therapeutic in Mouse Models of SCN1A and SCN8A Epilepsy

Sophie F. Hill,Paymaan Jafar-Nejad,Frank Rigo,Miriam H. Meisler

FRONTIERS IN NEUROSCIENCE (2023)

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Investigating 4R Tau Isoform Imbalance As a Mediator of Astrocyte Dysfunction in Tauopathies

Kathleen M. Schoch,Lubov A. Ezerskiy,Miwei Hu,Mariana Beltcheva,Frank Rigo,Timothy M. Miller

Alzheimer's &amp Dementiano. S13 (2023)

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