Pascal E Sanchez - Denali Therapeutics, Inc.

基本信息

浏览量：5

职业迁徙

个人简介

暂无内容

研究兴趣

论文共 48 篇作者统计合作学者相似作者

按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选

Targeting the Transferrin Receptor to Transport Antisense Oligonucleotides Across the Mammalian Blood-Brain Barrier

Scarlett J. Barker,Mai B. Thayer,Chaeyoung Kim,David Tatarakis,Matthew J. Simon, Rebekah Dial, Lizanne Nilewski,Robert C. Wells,Yinhan Zhou,Megan Afetian,Padma Akkapeddi,Alfred Chappell,Kylie S. Chew,Johann Chow, Allisa Clemens, Claire B. Discenza,Jason C. Dugas,Chrissa Dwyer,Timothy Earr,Connie Ha, Yvonne S. Ho,David Huynh, Edwin I. Lozano, Srini Jayaraman,Wanda Kwan,Cathal Mahon,Michelle Pizzo,Yaneth Robles-Colmenares,Elysia Roche, Laura Sanders, Alexander Stergioulis,Raymond Tong,Hai Tran,Joy Yu Zuchero,Anthony A. Estrada,Kapil Gadkar, Christopher M. M. Koth,Pascal E. Sanchez,Robert G. Thorne,Ryan J. Watts,Thomas Sandmann,Lesley A. Kane,Frank Rigo, Mark S. Dennis,Joseph W. Lewcock,Sarah L. Devos

SCIENCE TRANSLATIONAL MEDICINEno. 760 (2024)

引用0浏览0WOSSCIENCE引用

Engineering anti-amyloid antibodies with transferrin receptor targeting improves safety and brain biodistribution

Michelle E Pizzo,Edward D Plowey,Nathalie Khoury,Wanda Kwan, Jordan Abettan,Sarah L DeVos, Claire B Discenza,Timothy Earr,David Joy, Ming Lye-Barthel,Elysia Roche,Darren Chan,Jason C Dugas,Kapil Gadkar,René Meisner,Jennifer Sebalusky, Ana Claudia Silva Amaral,Isabel Becerra,Roni Chau,Johann Chow, Allisa J Clemens, Mark S Dennis,Joseph Duque, Laura Fusaro,Jennifer A Getz,Mihalis S Kariolis,Do Jin Kim,Amy Wing-Sze Leung,Hoang N Nguyen,Elliot R Thomsen,Pascal E Sanchez, Lu Shan,Adam P Silverman,Hilda Solanoy,Raymond Tong,Meredith E K Calvert, Ryan J Watts,Robert G Thorne, Paul H Weinreb, Dominic M Walsh,Joseph W Lewcock,Thierry Bussiere,Y. Joy Yu Zuchero

biorxiv（2024）

引用0浏览0引用

ETV:SGSH, a Brain-Penetrant Enzyme Transport Vehicle for SGSH, Improves Lysosomal and Microglial Morphology, Degeneration and Cognitive Behavior in MPS IIIA Mice

Shababa T. Masoud,Hoang Nguyen,Claire Discenza,David Joy,Jeffrey Simms,Iris Lo, You Young Chun,Julia Holtzman, Khishig Tsogtbaatar,Amy Wing-Sze Leung,Isabel Becerra,Elliot Thomsen,Audrey Gill,Yashas Rajendra,Alexander Seay,Mohammad Jafarnejad,Anna Bakardjiev,Meredith E. K. Calvert,Cathal S. Mahon,Robert Thorne, Steven Chessler,Kirk Henne,Pascal Sanchez,Annie Arguello

MOLECULAR GENETICS AND METABOLISMno. 2 (2024)

引用0浏览0引用

Reviewer #3 (public Review): DNL343 is an Investigational CNS Penetrant Eif2b Activator That Prevents and Reverses the Effects of Neurodegeneration Caused by the Integrated Stress Response

Ernie Yulyaningsih, J. H. Suh, Melania H. Fanok,Roni Chau,Hilda Solanoy,Ryan H. Takahashi,Anna I. Bakardjiev,Isabel Becerra, N. Butch Benitez,Chi‐Lu Chiu,Sonnet S. Davis,William E. Dowdle,Timothy Earr,Anthony A. Estrada,Audrey Gill,Connie Ha,Patrick C. G. Haddick,Kirk R. Henne,Martin Larhammar,Amy Wing-Sze Leung,Romeo Maciuca, Bahram Memarzadeh,Hoang N. Nguyen,Alicia Nugent,Maksim Osipov, Yingqing Ran, Kevin Rebadulla,Elysia Roche,Thomas Sandmann,Jing Wang,Joseph W. Lewcock, Kimberly Scearce‐Levie,Lesley A. Kane,Pascal E. Sanchez

openalex（2024）

引用0浏览0引用

Rescue of a Lysosomal Storage Disorder Caused by Grn Loss of Function with a Brain Penetrant Progranulin Biologic

Todd Logan,Matthew J. Simon,Anil Rana,Gerald M. Cherf,Ankita Srivastava,Sonnet S. Davis,Ray Lieh Yoon Low,Chi-Lu Chiu,Meng Fang,Fen Huang,Akhil Bhalla,Ceyda Llapashtica,Rachel Prorok,Michelle E. Pizzo,Meredith E. K. Calvert,Elizabeth W. Sun,Jennifer Hsiao-Nakamoto,Yashas Rajendra,Katrina W. Lexa,Devendra B. Srivastava,Bettina van Lengerich,Junhua Wang,Yaneth Robles-Colmenares,Do Jin Kim,Joseph Duque,Melina Lenser,Timothy K. Earr,Hoang Nguyen,Roni Chau,Buyankhishig Tsogtbaatar,Ritesh Ravi,Lukas L. Skuja,Hilda Solanoy,Howard J. Rosen,Bradley F. Boeve,Adam L. Boxer,Hilary W. Heuer,Mark S. Dennis,Mihalis S. Kariolis,Kathryn M. Monroe,Laralynne Przybyla,Pascal E. Sanchez,Rene Meisner,Dolores Diaz,Kirk R. Henne, Ryan J. Watts,Anastasia G. Henry,Kannan Gunasekaran,Giuseppe Astarita,Jung H. Suh,Joseph W. Lewcock,Sarah L. DeVos,Gilbert Di Paolo

Cell（2024）

引用101浏览0WOS引用

101

A TREM2‐activating Antibody with a Blood–brain Barrier Transport Vehicle Enhances Microglia Function

Pascal E. Sanchez

Alzheimer's &amp Dementiano. S21 (2023)

引用0浏览0引用

A TREM2-activating Antibody with a Blood–brain Barrier Transport Vehicle Enhances Microglial Metabolism in Alzheimer’s Disease Models

Bettina van Lengerich,Lihong Zhan,Dan Xia,Darren Chan,David Joy,Joshua I. Park,David Tatarakis,Meredith Calvert,Selina Hummel,Steve Lianoglou,Michelle E. Pizzo,Rachel Prorok,Elliot Thomsen,Laura M. Bartos,Philipp Beumers,Anja Capell,Sonnet S. Davis, Lis de Weerd,Jason C. Dugas,Joseph Duque,Timothy Earr,Kapil Gadkar,Tina Giese,Audrey Gill,Johannes Gnörich,Connie Ha,Malavika Kannuswamy,Do Jin Kim,Sebastian T. Kunte,Lea H. Kunze,Diana Lac,Kendra Lechtenberg,Amy Wing-Sze Leung,Chun-Chi Liang,Isabel Lopez,Paul McQuade, Anuja Modi, Vanessa O. Torres,Hoang N. Nguyen, Ida Pesämaa,Nicholas Propson,Marvin Reich,Yaneth Robles-Colmenares,Kai Schlepckow,Luna Slemann,Hilda Solanoy,Jung H. Suh,Robert G. Thorne, Chandler Vieira,Karin Wind-Mark, Ken Xiong,Y. Joy Yu Zuchero,Dolo Diaz,Mark S. Dennis,Fen Huang,Kimberly Scearce-Levie, Ryan J. Watts,Christian Haass,Joseph W. Lewcock,Gilbert Di Paolo,Matthias Brendel,Pascal E. Sanchez,Kathryn M. Monroe

Nature neuroscience (2023)

引用21浏览0WOSNATURE引用

ETV:SGSH, a brain-penetrant enzyme transport vehicle for SGSH, corrects heparan sulfate accumulation, lysosomal lipid storage and inflammation in MPS IIIA mouse brain

Shababa T. Masoud,Mohammad Jafarnejad,Hoang Nguyen,Buyankhishig Tsogtbaatar,Yashas Rajendra,Alexander Seay,Elliot R. Thomsen,Kensuke Yamanokuchi,Annie Arguello,Meng Fang,Cathal S. Mahon,Pascal Sanchez,Dolo Diaz,Anna Bakardjiev,Kirk Henne

Molecular Genetics and Metabolismno. 2 (2023): 107223-107223

引用0浏览0引用

加载更多

作者统计

合作学者

合作机构

D-Core

合作者
学生
导师

暂无相似学者，你可以通过学者研究领域进行搜索筛选

数据免责声明

页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果，我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问，可以通过电子邮件方式联系我们：report@aminer.cn