Paolo Sassone Corsi
教授
School of Pharmaceutical Sciences
College of Health Sciences, University of California;Department of Biological Chemistry, School of Medicine, University of California;Center for Epigenetics and Metabolism, School of Medicine, University of California;Department of Microbiology & Molecular Genetics, School of Medicine, University of California
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个人简介
Dr. Sassone-Corsi's major interest is concentrated on the mechanisms of signal transduction able to modulate nuclear functions and, in particular gene expression, chromatin remodeling and epigenetic control. These events have important consequences for the understanding of cellular proliferation, oncogenesis and differentiation. The stimulation of intracellular pathways and the activation of specific protein kinases lead to transcriptional regulation by changes in the phosphorylation state of nuclear factors. These act as final targets of different pathways and modulate expression from specific regulatory sites. The strength of these studies is particularly evident within physiological settings that have been investigated by this lab, the molecular control of circadian rhythms and the differentiation of male germ cells.
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Cell reportsno. 6 (2023): 112590-112590
bioRxiv (Cold Spring Harbor Laboratory) (2022)
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Molecular metabolism (2022): 101556-101556
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