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Sialic Acid Mediated Endothelial and Hepatic Uptake: A Mechanism Based Mathematic Model Elucidating the Complex Pharmacokinetics and Pharmacodynamics of Efmarodocokin Alfa, a Variably Glycosylated Fusion Protein

Xun Tao,Siddharth Sukumaran,Gizette Sperinde,Chang Liu,Michelle Irwin Beardsley, Peter Day, Matt Kalo, Ebehiremen Ayewoh,Hao Cai,Yehong Wang,Inyoung Jun, Kyle Hirst,Van Nguyen,Shan Chung,Donna Lee,Annemarie Lekkerkerker,Eric Stefanich

Journal of pharmaceutical sciences（2024）

引用 0|浏览15
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关键词
Pharmacokinetics,Pharmacodynamics,Glycoprotein uptake,Sialic acid,Mathematical model
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