181 Presystemic Elimination
IUPAC Standards Online
University of Toledo | Flinders University | Bayer (Germany) | University of Florida | University of Surrey | University of Aberdeen | University of Arkansas for Medical Sciences | Northwood University | Daiichi University of Pharmacy | Wayne State University | University of Minnesota | Esteve Química (Spain) | MPI Research (United States) | Vrije Universiteit Amsterdam | Eli Lilly (United States)
Abstract
This project originated more than 15 years ago with the intent to produce a glossary of drug metabolism terms having definitions especially applicable for use by practicing medicinal chemists. A first-draft version underwent extensive beta-testing that, fortuitously, engaged international audiences in a wide range of disciplines involved in drug discovery and development. It became clear that the inclusion of information to enhance discussions among this mix of participants would be even more valuable. The present version retains a chemical structure theme while expanding tutorial comments that aim to bridge the various perspectives that may arise during interdisciplinary communications about a given term. This glossary is intended to be educational for early stage researchers, as well as useful for investigators at various levels who participate on today’s highly multidisciplinary, collaborative small molecule drug discovery teams.
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Key words
Drug Target Identification
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