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181 Presystemic Elimination

IUPAC Standards Online

University of Toledo | Flinders University | Bayer (Germany) | University of Florida | University of Surrey | University of Aberdeen | University of Arkansas for Medical Sciences | Northwood University | Daiichi University of Pharmacy | Wayne State University | University of Minnesota | Esteve Química (Spain) | MPI Research (United States) | Vrije Universiteit Amsterdam | Eli Lilly (United States)

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Abstract
This project originated more than 15 years ago with the intent to produce a glossary of drug metabolism terms having definitions especially applicable for use by practicing medicinal chemists. A first-draft version underwent extensive beta-testing that, fortuitously, engaged international audiences in a wide range of disciplines involved in drug discovery and development. It became clear that the inclusion of information to enhance discussions among this mix of participants would be even more valuable. The present version retains a chemical structure theme while expanding tutorial comments that aim to bridge the various perspectives that may arise during interdisciplinary communications about a given term. This glossary is intended to be educational for early stage researchers, as well as useful for investigators at various levels who participate on today’s highly multidisciplinary, collaborative small molecule drug discovery teams.
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Drug Target Identification
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要点】:本项目旨在创建一个针对药物代谢术语的词汇表,其定义特别适用于执业药物化学家,并通过国际多学科参与者的广泛反馈进行优化,旨在促进跨学科交流和理解。

方法】:通过制作初稿并进行广泛的国际测试,收集不同学科的意见反馈,不断优化和完善词汇表,增强其教育性和实用性。

实验】:本文未涉及具体的实验过程,而是通过beta测试和反馈来改进药物代谢术语的词汇表,未提及使用特定数据集。