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Fructose-1,6-bisphosphatase is a Nonenzymatic Safety Valve That Curtails AKT Activation to Prevent Insulin Hyperresponsiveness.

Li Gu,Yahui Zhu,Kosuke Watari,Maiya Lee,Junlai Liu,Sofia Perez,Melinda Thai,Joshua E. Mayfield,Bichen Zhang,Karina Cunha e Rocha,Fuming Li,Laura C. Kim,Alexander C. Jones,Igor H. Wierzbicki, Xiao Liu,Alexandra C. Newton,Tatiana Kisseleva,Jun Hee Lee,Wei Ying,David J. Gonzalez,Alan R. Saltiel,M. Celeste Simon,Michael Karin

Cell Metabolism（2023）

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关键词
FBP1,AKT,hepatomegaly,hepatosteatosis
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