Trivalent PROTACs Enhance Protein Degradation Via Combined Avidity and Cooperativity

Satomi Imaide,Kristin M. Riching,Nikolai Makukhin,Vesna Vetma,Claire Whitworth,Scott J. Hughes,Nicole Trainor,Sarah D. Mahan,Nancy Murphy,Angus D. Cowan,Kwok-Ho Chan,Conner Craigon,Andrea Testa,Chiara Maniaci,Marjeta Urh,Danette L. Daniels,Alessio Ciulli

Nature chemical biology（2021）

引用 80|浏览36

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Mechanism of action,Pharmacology,Small molecules,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry

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