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Annulation Reaction Enables the Identification of an Exocyclic Amide Tricyclic Chemotype As Retinoic Acid Receptor-Related Orphan Receptor Gamma (rorγ/rorc) Inverse Agonists

David Marcoux,Myra Beaudoin Bertrand,Carolyn A. Weigelt,Shiuhang Yip,Michael Galella,Hyunsoo Park,Dauh-Rurng Wu,Jinhong Wang,Melissa Yarde,Mary Ellen Cvijic,Sha Li,John Hynes,Joseph A. Tino,Qihong Zhao,T. G. Murali Dhar

Bioorganic & medicinal chemistry letters（2020）

引用 5|浏览75
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关键词
Annulation,Cyclopentane,Exocyclic amide,ROR gamma t,IL-17
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