Chrome Extension
WeChat Mini Program
Use on ChatGLM

Author Correction: Targeted NUDT5 Inhibitors Block Hormone Signaling in Breast Cancer Cells

Nature communications(2019)SCI 1区

Science for Life Laboratory | Centre de Regulació Genòmica (CRG) | Department of Biochemistry and Biophysics | Uppsala University Drug Optimization and Pharmaceutical Profiling Platform | Chemical Biology Consortium Sweden

Cited 2|Views5
Abstract
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
More
Translated text
Key words
Breast cancer,Drug discovery and development,Screening,Target validation,Science,Humanities and Social Sciences,multidisciplinary
PDF
Bibtex
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn
Chat Paper

要点】:本文报道了一种针对NUDT5的抑制剂,能够阻断乳腺癌细胞中的激素信号,具有潜在的抗癌治疗作用。

方法】:作者通过分子对接和动力学模拟方法,设计并筛选出具有潜在抑制活性的NUDT5抑制剂。

实验】:实验在乳腺癌细胞系MCF-7中进行,使用的数据集为抑制剂对NUDT5活性的抑制效果数据,结果显示NUDT5抑制剂能够有效阻断激素信号,抑制乳腺癌细胞生长。