Targeted High-Throughput Sequencing of Candidate Genes for Chronic Obstructive Pulmonary Disease

Hans Matsson,Cilla Söderhäll,Elisabet Einarsdottir,Maxime Lamontagne,Sanna Gudmundsson,Helena Backman,Anne Lindberg,Eva Rönmark,Juha Kere,Don Sin,Dirkje S. Postma,Yohan Bossé,Bo Lundbäck,Joakim Klar

BMC pulmonary medicine（2016）

引用 23|浏览36

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摘要

Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD.

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关键词

COPD,Sequencing,eQTL,Association,Lung development,CHRNA5

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