Ni2+ and Cu2+ complexes of a phenanthroline-based ligand bind to G-quadruplexes at non-overlapping sites.
CHEMICAL COMMUNICATIONS(2013)
摘要
Transition metal complexes allow fine tuning of DNA binding affinity and selectivity. Here we report on the nucleic acid recognition properties of a phenanthroline-based ligand coordinated to Ni2+ or Cu2+. The resulting complexes clearly bind to telomeric G-quadruplexes at different sites according to the nature of the bound metal ion.
更多查看译文
关键词
ligand bind,complexes,cu2+,phenanthroline-based,g-quadruplexes,non-overlapping
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要