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杨照,教授,博士生导师,国家自然科学基金优秀青年基金获得者,山东省“泰山学者”青年专家,山东大学齐鲁青年学者。主要从事重大疾病相关G蛋白偶联受体(GPCR)的内源性配体发现和调控机制研究,通过靶向配体开发实现对GPCR的功能调控,具体学术成绩包括:(1)发现了代谢性疾病中多种孤儿受体的内源性配体,阐明了其功能及信号转导机制(Cell Metab,2022; Nat Chem Biol,2022; PNAS,2021);(2)揭示了GPCR信号复合物形成的调控机制,包括GPCR的磷酸化编码和内源性别构调控等(Cell Res,2021; Adv Sci,2023; Cell Death Dis,2018);(3)发展了识别GPCR隐式别构调控位点的新策略,为靶向GPCR的别构配体设计和开发提供了新的思路(Nat Chem Biol,2023; Nat Commun,2021; J Biol Chem,2021)。研究成果发表在 Cell Metab,Nat Chem Biol(×2),Cell Res,PNAS 和 Nat Commun 等知名杂志,其中2篇被选为当期杂志封面,2篇论文由同期杂志配发专题评述,1篇被评为高被引论文。主持多项国家自然科学基金项目和山东省自然科学基金项目,作为项目骨干参与国家重点研发计划项目。
Research Interests
Papers共 14 篇Author StatisticsCo-AuthorSimilar Experts
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Shen-Ming Huang,Meng-Yao Xiong,Lei Liu,Jianqiang Mu,Ming-Wei Wang,Ying-Li Jia, Kui Cai,Lu Tie,Chao Zhang,Sheng Cao,Xin Wen,Jia-Le Wang,Sheng-Chao Guo,Yu Li,Chang-Xiu Qu,Qing-Tao He,Bo-Yang Cai,Chenyang Xue,Shiyi Gan, Yihe Xie,Xin Cong,Zhao Yang,Wei Kong,Shuo Li,Zijian Li,Peng Xiao,Fan Yang,Xiao Yu,You-Fei Guan,Xiaoyan Zhang,Zhongmin Liu,Bao-Xue Yang,Yan Du,Jin-Peng Sun
Proceedings of the National Academy of Sciencesno. 30 (2023)
Jie Cheng,Zhao Yang,Xiao-Yan Ge,Ming-Xin Gao,Ran Meng, Xin Xu, Yu-Qi Zhang, Rui-Zhe Li,Jing-Yu Lin,Zhao-Mei Tian,Jin Wang,Shang-Lei Ning,Yun-Fei Xu,Fan Yang,Jing-Kai Gu,Jin-Peng Sun,Xiao Yu
Cell metabolismno. 2 (2022): 240-255.e10
Trends in cell biologyno. 6 (2022): 463-476
Yi Fu,Yaqian Huang,Zhao Yang,Yufei Chen,Jingang Zheng,Chenfeng Mao,Zhiqing Li,Zhixin Liu,Bing Yu,Tuoyi Li,Meili Wang,Chanjuan Xu,Yiwei Zhou,Guizhen Zhao,Yiting Jia,Wei Guo,Xin Jia,Tao Zhang, Li Li,Ziyi Liu,Shengchao Guo,Mingliang Ma,Heng Zhang,Bo Liu,Junbao Du,Wengong Wang,Chaoshu Tang,Pei Gao,Qingbo Xu,Xian Wang,Jianfeng Liu, Junying Sun,Wei Kong
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Author Statistics
#Papers: 14
#Citation: 402
H-Index: 9
G-Index: 12
Sociability: 5
Diversity: 2
Activity: 33
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