Dr. Seo is interested in deciphering the roles of essential metals in related disorders and in developing new diagnostic and therapeutic strategies for treating disorders of metal imbalance. She aspires to contribute to the field of metal biology with her unique perspective as a cell biologist and biochemist. Dr. Seo’s current research focuses on the new roles of manganese in a variety of traits and diseases, including intestinal, metabolic, and neurodevelopmental disorders. Dr. Seo also has made substantial progress in developing new small molecules to understand and treat iron imbalance disorders. Dr. Seo employs combinatorial approaches, encompassing mouse reverse genetics and phenotyping, intestinal organoid cultures derived from genetically engineered mice, cell culture model of neuronal development, and functional genomics utilizing next-generation sequencing.