Research
‘Studying one host gene is good; carry along all genes is even better.’ – Jan Carette
Functional genomic approaches such as genome-scale CRISPR editing, Haploid genetic screen, and genome-wide RNAi have continuously driven the discovery of new knowledge about many emerging and re-merging viruses. We leverage the awesome power of functional genomics to unbiasedly uncover host factors essential for infection and pathogenesis of clinically significant RNA viruses. Our discovery will shed light on the underlying molecular mechanisms of viral infections and diseases, and we hope to provide new knowledge for improving vaccine designs and development and innovating antiviral strategies.