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Dr. Kitamura’s current research focuses on genetic and epigenetic control of leukemogenesis, in particular the roles of mutations in epigenetic regulators including EZH2, TET2, and ASXL1. His research has made some exciting discoveries. "Mutations in EZH2, TET2 or ASXL1 alone induce MDS-like symptoms in mouse models. We identified one of the underlying molecular mechanisms of ASXL1 mutation-induced MDS,” Dr. Kitamura explains. In addition, Dr. Kitamura contributes to the field by offering a cytokine-dependent TF-1 cell line which he established from one of his patient in 1987, as well as a retrovirus vector pMX and a packaging cell line PLAT-E. These tools are now widely used by the scientific community.
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[Rinsho ketsueki] The Japanese journal of clinical hematologyno. 4 (2024): 209-221
Kohei Iida, Mayuko Nakanishi, Jakushin Nakahara,Shuhei Asada, Tomoya Isobe,Tomohiro Yabushita,Manabu Ozawa,Yasuhiro Yamada,Toshio Kitamura,Keita Yamamoto,Susumu Goyama
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CANCER SCIENCE (2023): 1709-1709
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Tomohiro Yabushita,Takumi Chinen,Atsuya Nishiyama,Shuhei Asada, Ken Yamamoto, Nobuko Sato,Yutaka Enomoto, Keiko Katoh,Kaori Saitoh,Takamasa Ishikawa,Tomoyoshi Soga,Yasuhito Nannya,
HemaSphereno. S3 (2023): e20270ec-e20270ec
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CANCER SCIENCE (2023): 721-721
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Atsushi Tanaka,Koutarou Nishimura, Wataru Saika,Ayana Kon,Yui Koike, Hiromi Tatsumi,June Takeda,Masaki Nomura,Weijia Zang,Manabu Nakayama, Masashi Matsuda,Hiromi Yamazaki,
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