We are employing diverse technologies to identify, study and map properties and relationships among individual functional units in the genome. Projects in the lab encompass gene expression studies in organisms ranging from yeast to mouse, experimental identification of functional units in the genome sequence, global analysis of DNA binding and RNA processing activities, and genome-scale characterization of proteins via the construction of extensive reagent collections. Most of our work utilizes microarray technology and involves computational data analysis. We collaborate extensively with groups at the University of Toronto, elsewhere in Canada, and internationally.