Thibault Joseph William Jacques Dit Lapierre - Transfer Group Anti-infectives, Leibniz Institute for Natural Product Research and Infection Biology-Leibniz-HKI

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New Drug Discovery Strategies for the Treatment of Benznidazole-Resistance in Trypanosoma Cruzi, the Causative Agent of Chagas Disease

Silvane Maria Fonseca Murta, Pedro Augusto Lemos Santana,Thibault Joseph William Jacques Dit Lapierre,André Berndt Penteado, Marissa El Hajje, Thabata Corazza Navarro Vinha,Daniel Barbosa Liarte,Mariana Laureano de Souza,Gustavo Henrique Goulart Trossini,Celso de Oliveira Rezende Júnior,Renata Barbosa de Oliveira,Rafaela Salgado Ferreira

Expert opinion on drug discoveryno. 6 (2024): 741-753

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Synthesis, Design, and Optimization of a Potent and Selective Series of Pyridylpiperazines As Promising Antimalarial Agents

Douglas Davison da Silva Oliveira, Franciarli Paz,Nicolas Peterson Ferreira Brito,Arne Kruger,Ana Clara Cassiano Martinho,Thibault Joseph William Jacques Dit Lapierre,Felipe de Oliveira Souza,Vinicius G. Maltarollo,Thales Kronenberger, Marina Sena Mendes,Maria Cristina Nonato,Eduardo Jorge Pilau,Carsten Wrenger,Gerhard Wunderlich,Celso de Oliveira Rezende Junior

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024)

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Discovery of Arylpiperazines with Broad-Spectrum Antimicrobial Activity and Favorable Pharmacokinetic Profiles

Douglas Davison da Silva Oliveira,Nagela Bernadelli Sousa Silva,Thibault Joseph William Jacques Dit Lapierre, Sara Lemes de Souza,Nícolas Peterson Ferreira Brito,Ana Clara Cassiano Martinho,Renieidy Flávia Clemente Dias,Danilo Nascimento Farago,Simone Michelan-Duarte,Rafael Consolin Chelucci, Mariza Gabriela Faleiro de Moura Lodi Cruz,Daniela de Melo Resende,Adriano D Andricopulo,Silvane Maria Fonseca Murta,Leonardo L G Ferreira,Carlos Henrique Gomes Martins,Celso de Oliveira Rezende Júnior

Chemistry & biodiversitypp.e202402100-e202402100, (2024)

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Evaluation and Discovery of Novel Benzothiazole Derivatives As Promising Hits Against Leishmania Infantum

Thibault Joseph William Jacques Dit Lapierre,Danilo Nascimento Farago, Mariza Gabriela Faleiro de Moura Lodi Cruz,Daniela de Melo Resende, Adriane Cristina Rosa de Oliveira, Brenda Rosa Macedo dos Santos,Felipe de Oliveira Souza,Simone Michelan-Duarte,Rafael C. Chelucci,Adriano D. Andricopulo,Leonardo L. G. Ferreira,Eduardo Jorge Pilau,Silvane Maria Fonseca Murta,Celso de Oliveira Rezende Junior

CHEMICAL BIOLOGY & DRUG DESIGN（2024）

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Modulation of the Meisenheimer Complex Metabolism of Nitro-Benzothiazinones by Targeted C-6 Substitution

Francois Keiff,Freddy A. Bernal, Melanie Joch,Thibault J. W. Jacques Dit Lapierre, Yan Li,Phil Liebing,Hans-Martin Dahse,Ivan Vilotijevic,Florian Kloss

COMMUNICATIONS CHEMISTRYno. 1 (2024)

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Advances in Breast Cancer Drug Discovery: A Review of Therapeutic Strategies and Studies Involving Photosensitizers, Caged Xanthones and Thiosemicarbazones Derivatives

Douglas D. S. Oliveira,Thibault J. W. Jacques Dit Lapierre,Fernanda C. Silva, Ieda V. Cunha,Rafael A. C. Souza,Patricia A. Matos, Gustavo M. Almeida,Carolina G. Oliveira,Thaise G. Araujo,Tayana M. Tsubone, Celso O. Rezende Jr

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2023)

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Hit-to-lead Optimization of a Pyrazinylpiperazine Series Against Leishmania Infantum and Leishmania Braziliensis

Thibault Joseph William Jacques Dit Lapierre, Mariza Gabriela Faleiro de Moura Lodi Cruz,Nicolas Peterson Ferreira Brito,Daniela de Melo Resende,Felipe de Oliveira Souza,Eduardo Jorge Pilau, Meryck Felipe Brito da Silva,Bruno Junior Neves,Silvane Maria Fonseca Murta,Celso de Oliveira Rezende Junior

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2023)

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Design and Synthesis of Benzofuran- and Naphthalene-Fused Thiazinones As Antimycobacterial Agents

Francois Keiff,Thibault J. W. Jacques dit Lapierre,Freddy A. Bernal,Florian Kloss

Archiv der Pharmazieno. 11 (2023)

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Molecular Targets for Chagas Disease: Validation, Challenges and Lead Compounds for Widely Exploited Targets

Mariana Laureano de Souza,Thibault Joseph William Jacques Dit Lapierre,Gabriel Vitor de Lima Marques,Witor Ribeiro Ferraz,André Berndt Penteado,Gustavo Henrique Goulart Trossini,Silvane Maria Fonseca Murta,Renata Barbosa de Oliveira, Celso de Oliveira Rezende,Rafaela Salgado Ferreira

Expert opinion on therapeutic targetsno. 10 (2023): 911-925

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Synthesis, Design, and Structure‐Activity Relationship of a Benzenesulfonylpiperazine Series Against Trypanosoma Cruzi

Ana Clara Cassiano Martinho,Daniela de Melo Resende,Emanuelly Silva Landin,Thibault Joseph William Jacques Dit Lapierre,Talita Cristina Diniz Bernardes,Luan Carvalho Martins,Rafaela Salgado Ferreira,Silvane Maria Fonseca Murta,Celso de Oliveira Rezende Junior

ChemMedChemno. 19 (2022)

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