Steven T Laing - Dept Safety Assessment, Genentech Inc

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论文共 25 篇作者统计合作学者相似作者

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A Proof-of-concept Rat Toxicity Study Highlights the Potential Utility and Challenges of Virtual Control Groups

Roxanne Andaya,Ruth Sullivan,Tony Pourmohamad, Matt Hayes,Pierre Maliver,Steven Laing,Catrin Hasselgren,Noel Dybdal,Adeyemi O. Adedeji,Lennart T. Anger

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATIONno. 4 (2024): 647-659

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Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Complex in Vitro Model Characterization for Context of Use in Toxicologic Pathology: Use Cases by Collaborative Teams of Biologists, Bioengineers, and Pathologists

Nadine Stokar-Regenscheit,Luisa Bell,Brian Berridge,Daniel Rudmann,Danilo Tagle, Passley Hargrove-Grimes,Dirk Schaudien,Kerstin Hahn,Julia Kühnlenz,Randolph S Ashton,Min Tseng,Mike Reichelt,Steven T Laing,Tomomi Kiyota,Ronnie Chamanza,Radhakrishna Sura,Lindsay Tomlinson

Toxicologic pathologyno. 2-3 (2024): 123-137

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Airway Tryptase Levels Inform the Lack of Clinical Efficacy of the Tryptase Inhibitor MTPS9579A in Asthma

Horace Rhee,Lindsay M. Henderson,Rebecca N. Bauer,Kit Wong,Tracy L. Staton,David F. Choy,Prajna Banerjee,Victor Poon,Kenta Yoshida, Chen, Keyi Long,Gizette Sperinde,Steven T. Laing,Nicholas S. Jones, Sara B. Glickstein,Parul Dayal,Alice Fong,Ajit Dash,Grazyna Pulka,Brian Leaker,Dave Singh,Peter Bradding

ALLERGY (2024)

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Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys

Hao Cai, Xun Tao,Jeongsup Shim,Rebecca N. Bauer,Meire Bremer, Wei Bu, Jason LaMar, Rachel Basile,Edward Dere, Tien Nguyen,Steven Laing,Pamela Chan,Tangsheng Yi,James T. Koerber,Gizette Sperinde,Eric Stefanich

AAPS JOURNALno. 4 (2023)

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Spontaneous Findings in the Reproductive System of Sexually Mature Male Cynomolgus Macaques

Justin D. Vidal,Manoj Bhaskaran, Mary Carsillo, Steve Denham, Olivia Dubay,Steven Laing,Balasubramanian Manickam, Stephanie Phillips,Jonathan Werner,Armando R. Irizarry Rovira

Toxicologic pathology（2022）

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Animal Models in Toxicologic Research: Nonhuman Primate

Jennifer A. Chilton,Steven T. Laing,Alys Bradley

Haschek and Rousseaux's Handbook of Toxicologic Pathologypp.777-809, (2022)

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Fab-Nanolipoprotein Conjugate Causes Vitreous Opacity and Cataracts Following a Single Intravitreal Administration in New Zealand White Rabbits

Nardos G. Tassew,Steven T. Laing,Whitney Shatz,Susan R. Crowell,Kelly M. Loyet,Chris Schuetz,Craig Blanchette

TOXICOLOGIC PATHOLOGY（2021）

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An Integrated Approach for Characterizing Immunogenic Responses Toward a Bispecific Antibody

Sivan Cohen,Shan Chung,Christoph Spiess,Victor Lundin,Eric Stefanich,Steven T. Laing,Vanessa Clark,Jochen Brumm,Ying Zhou,Catherine Huang,Joyce Guerrero,Srividya Myneni,Rajbharan Yadav,Ketevan Siradze,Kun Peng

mAbs（2021）

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Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins

Steven T. Laing,Nardos Tassew,Devin Tesar, Yue Wang,Susan R. Crowell,Julia Gray,Mandy Kwong,Kelly M. Loyet,Roxanne Andaya,Aija Kusi,Robert F. Kelley

Toxicologic pathology（2020）

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