Sidhartha Mahali

Laboratory of Immunology Centre for DNA Fingerprinting &Diagnostics, Nampally, Hyderabad 500001, India.

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基本信息

Career Trajectory

Bio

My primary research interest lies investigating the molecular mechanism underlying neurodegenerative disorders. My academic career so far has provided me with an excellent background in the cell signaling pathways associated with a number of cellular processes such as aging, autophagy-lysosomal machinery, cytoskeleton modulation and cellular metabolism. Trained in culturing and generating iPSC-derived microglia, macrophages, neurons and astrocytes.

Research Interests

Papers共 21 篇Author StatisticsCo-AuthorSimilar Experts

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合作机构

Conserved Gene Signatures Shared among MAPT Mutations Reveal Defects in Calcium Signaling

Miguel A. A. Minaya,Sidhartha Mahali,Abhirami K. K. Iyer,Abdallah M. M. Eteleeb,Rita Martinez, Guangming Huang,John Budde,Sally Temple,Alissa L. L. Nana,William W. W. Seeley,Salvatore Spina,Lea T. T. Grinberg,Oscar Harari,Celeste M. M. Karch

Frontiers in Molecular Biosciences（2023）

Cited1Views0WOSBibtex

Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

Fabia Filipello,Shih Feng You,Sidhartha Mahali,Abhirami Kannan Iyer,Rita Martinez,Olena Korvatska,Wendy H Raskind,Bryan Bollman,Claudia Cantoni,Luca De Feo,Laura Ghezzi,Miguel Minaya,Anil G Cashikar,Jun-Ichi Satoh,Wandy Beatty,Marina Cella,Laura Piccio,Celeste M Karch

Acta neuropathologicano. 6 (2022): 749-772

Cited7Views0WOSBibtex

Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration

Sidhartha Mahali,Rita Martinez,Melvin King,Anthony Verbeck,Oscar Harari,Bruno A. Benitez,Kanta Horie,Chihiro Sato,Sally Temple,Celeste M. Karch

TRANSLATIONAL PSYCHIATRY（2022）

Cited5Views0WOSNATUREBibtex

Functional characterization of hiPSCs-derived glial cells and neurons from patients harboring a TREM2 loss of function mutation

Fabia Filipello,Shih-Feng You,Rita Martinez,Olena Korvatska,Wendy H Raskind,Sidhartha Mahali,Laura Ghezzi,Beatty Wandy,Marina Cella,Laura Piccio,Celeste M Karch

Alzheimers Dement（2021）

Cited0Views0WOSBibtex

Defective Proteostasis in Patient-Derived Ipsc-Astrocytes and Neurons Carrying a MAPT IVS10+16 Mutation

Sidhartha Mahali,Celeste Karch

Alzheimer s & Dementia（2021）

Cited2Views0WOSBibtex

ELAVL4, Splicing, and Glutamatergic Dysfunction Precede Neuron Loss in MAPT Mutation Cerebral Organoids

Kathryn R. Bowles,M. Catarina Silva,Kristen Whitney,Taylor Bertucci,Joshua E. Berlind,Jesse D. Lai,Jacob C. Garza,Nathan C. Boles,Sidhartha Mahali,Kevin H. Strang,Jacob A. Marsh,Cynthia Chen,Derian A. Pugh,Yiyuan Liu, Ronald E. Gordon,Susan K. Goderie,Rebecca Chowdhury,Steven Lotz,Keith Lane,John F. Crary,Stephen J. Haggarty,Celeste M. Karch,Justin K. Ichida,Alison M. Goate,Sally Temple

Cell（2021）

Cited77Views0WOSBibtex

Glutamatergic Dysfunction Precedes Neuron Loss in Cerebral Organoids with MAPT Mutation

Kathryn R. Bowles,M. Catarina Silva,Kristen Whitney,Taylor Bertucci,Jacob C. Garza,Nathan C. Boles,Kevin H. Strang,Sidhartha Mahali,Jacob A. Marsh,Cynthia Chen,Derian A. Pugh,Yiyuan Liu,Joshua E. Berlind,Jesse D. Lai,Susan K. Goderie,Rebecca Chowdhury,Steven Lotz,Keith Lane,Khadijah Onanuga,Celeste M. Karch,Justin K. Ichida,John F. Crary,Stephen J. Haggarty,Alison M. Goate,Sally Temple

bioRxiv (Cold Spring Harbor Laboratory) (2021)

Cited1Views0Bibtex

O3‐07‐02: LYSOSOMAL DYSFUNCTION IN STEM CELL MODELS OF TAUOPATHY

Sidhartha Mahali,Shan Jiang,Simon Hsu,Bruno Benitez,Oscar Harari,Carlos Cruchaga,Celeste M. Karch

Alzheimer's &amp Dementia（2019）

Cited0Views0Bibtex

LYSOSOMAL DYSFUNCTION AND ALTERED TAU METABOLISM IN STEM CELL MODELS OF AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE

Sidhartha Mahali,Simon Hsu,Bruno Benitez,Rita Martinez,Alison M. Goate,Celeste Karch

Alzheimer's & dementiano. 7S_Part_12 (2018)

Cited0Views0Bibtex

A natural xanthone increases catalase activity but decreases NF-kappa B and lipid peroxidation in U-937 and HepG2 cell lines

Binay K. Sahoo,Adeel H. Zaidi,Pankaj Gupta,Raveendra B. Mokhamatam,Nune Raviprakash,Sidhartha K. Mahali,Sunil K. Manna

European Journal of Pharmacology（2015）

Cited19Views0WOSBibtex

Author Statistics

#Papers: 21

#Citation: 264

H-Index: 7

G-Index: 13

Sociability: 4

Diversity: 2

Activity: 98

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