Sharon Lin - KSQ Therapeut | 人才画像

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Abstract 20: KSQ-001EX: An engineered TIL therapy manufactured from a clinical-scale, feeder-free process for the treatment of solid tumor indications

Sharon Lin, Gustavo Martinez,Marie-Andrée Forget, Katrina Adlerz,Mitali Ghose,Leila Williams,Paul Dunbar, Frank Thompson,Fiona Sharp,Hugh Gannon,Conor Calnan,Ashish Yeri,Dipen Sangurdekar, Donald Sakellariou-Thompson,Samantha Fix, Tamara Griffith, Ellie Jafari, Jane Zulovich,Priya Balasubramanian,Erin Willert,MIcah Benson,Chantale Bernatchez,Karrie Ka Wai Wong

Cancer Researchno. 6_Supplement (2024): 20-20

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Abstract 20: KSQ-001EX: an Engineered TIL Therapy Manufactured from a Clinical-Scale, Feeder-Free Process for the Treatment of Solid Tumor Indications

Sharon Lin, G. Martínez,Marie‐Andrée Forget, Katrina Adlerz,Mitali Ghose,Leila J. Williams, P. Rod Dunbar, D.J. Thompson,Fiona A. Sharp,Hugh Gannon,Conor Calnan,Ashish Yeri,Dipen Sangurdekar,Donald A. Sakellariou-Thompson,Samantha M. Fix, Tamara Griffith, Ellie Jafari, Jane Zulovich, Priya Balasubramanian,Erin Willert,Micah J. Benson,Chantale Bernatchez,Karrie Wong

Cancer researchno. 6_Supplement (2024): 20-20

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Rational Design of a SOCS1-edited Tumor-Infiltrating Lymphocyte Therapy Using CRISPR/Cas9 Screens

Michael R. Schlabach,Sharon Lin, Zachary R. Collester,Christopher Wrocklage,Sol Shenker,Conor Calnan,Tianlei Xu,Hugh S. Gannon,Leila J. Williams, Frank Thompson, Paul R. Dunbar,Robert A. Lamothe,Tracy E. Garrett,Nicholas Colletti,Anja F. Hohmann,Noah J. Tubo,Caroline P. Bullock,Isabelle Le Mercier,Katri Sofjan,Jason J. Merkin,Sean Keegan,Gregory V. Kryukov, Caroline Dugopolski,Frank Stegmeier,Karrie Wong,Fiona A. Sharp,Louise Cadzow,Micah J. Benson

biorxiv（2023）

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Expresstm: an accelerated process for the manufacture of ksq-001, a crispr/cas9-edited etiltm product

Sharon Lin,Leila Williams,Mitali Ghose,Hugh Gannon,Conor Calnan,Angelina Pizzo,Pei-Lun Kao,Mallory Brady,Katri Sofjan,Anne Dodson,Sol Shenker,Michael Schlabach,Fiona Sharp,Frank Stegmeier,Micah Benson,Karrie Wong

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2022): A270-A270

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255 ExPRESS^TM: An accelerated process for the manufacture of KSQ-001, a CRISPR/Cas9-edited eTIL^TMproduct

Regular and Young Investigator Award Abstracts (2022)

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Manufacture of ksq-001, a crispr/cas9engineered til (etil) therapy, for the treatment of head and neck squamous cell carcinoma

Karrie Wong,Leila Williams, Nick Constant,Mitali Ghose,Sharon Lin, Frank Thompson,Conor Calnan,Fiona Sharp,Sean Donnelly,Charles Quinn,Glenn Hanna,Frank Stegmeier,Micah Benson

Regular and Young Investigator Award Abstracts（2022）

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297 Manufacture of KSQ-001, a CRISPR/Cas9-engineered TIL (etil) Therapy, for the Treatment of Head and Neck Squamous Cell Carcinoma

Karrie Wong,Leila J. Williams, Nick Constant,Mitali Ghose,Sharon Lin, D.J. Thompson,Conor Calnan,Fiona A. Sharp,Seán Donnelly,Charles T. Quinn,Glenn J. Hanna,Frank Stegmeier,Micah J. Benson

Regular and Young Investigator Award Abstracts (2022)

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186 Development of KSQ-001, an Engineered TIL (etil) Therapy for Solid Tumors Through CRISPR/Cas9-mediated Editing of SOCS1

Karrie Wong,Sharon Lin,Christopher Wrocklage,Katri Sofjan,Leila Williams,Mallory Brady,Nicholas Colletti,Noah Tubo,Hugh Gannon, Robert LaMothe,Tianlei Xu, Tracy VandenBerg,Sol Shenker, Caroline Dugopolski,Frank Stegmeier,Louise Cadzow,Michael Schlabach,Micah Benson

Regular and Young Investigator Award Abstracts（2021）

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204 KSQ-004: Unbiased Pair-Wise Discovery of SOCS1 and Regnase-1 As the Top CRISPR/Cas9 Dual-Edit Combination Enhancing in Vivo TIL Potency Against Solid Tumors

Karrie Wong,Christopher Wrocklage,Sharon Lin,Isabelle Le Mercier,Caroline Bullock,Louise Cadzow,Anja F. Hohmann, Stephen H. Shenker,Katri Sofjan,Leila J. Williams,Gregory V. Kryukov,Conor Calnan,Frank Stegmeier,Micah J. Benson,Michael R. Schlabach

Journal for immunotherapy of cancer（2021）

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Nuclear Monomeric Integrin Αv in Cancer Cells is a Coactivator Regulated by Thyroid Hormone

Hung-Yun Lin,Yee-Fun Su,Meng-Ti Hsieh,Sharon Lin,Ran Meng,David London,Cassie Lin,Heng-Yuan Tang,Jaulang Hwang,Faith B. Davis,Shaker A. Mousa,Paul J. Davis

The FASEB journal（2013）

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