One of the main areas of research within my group involves identifying and characterizing specific transport proteins that are required by cells to fulfill their metabolic needs. Within this objective, we aim to understand what drives selective transporter expression in disease, how transporters function in specific physiological contexts, and how we can target the unique metabolic demands of cancer. We utilize biochemical and molecular biology techniques and develop quantitative mass spectrometry-based methods that include targeted and discovery metabolomics, stable-isotope tracing, and metabolic flux analysis to characterize the fate of key nutrients in diseased cells.