Samuel Deutsch - University of Geneva, University Hospitals of Geneva

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Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic Mrna Delivery Via Diverse Library Clustering and Structural Parametrization

Elizabeth R. Webster, Nicole E. Peck, Juan Diego Echeverri, Shima Gholizadeh, Wei-Lun Tang, Rinette Woo, Anushtha Sharma,Weiqun Liu,Chris S. Rae,Adrienne Sallets, Gowrisudha Adusumilli,Kannan Gunasekaran,Ole A. W. Haabeth,Meredith Leong,Ronald N. Zuckermann,Samuel Deutsch,Colin J. Mckinlay

ACS NANOno. 33 (2024): 22181-22193

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Abstract 6536: Enhanced membrane stability of mRNA nanoparticle derived TNFSF14 results in superior T-cell and NK cell stimulation

Adrienne Sallets,Weiqun Liu,Meredith L. Leong,Ruben Prins,Diane M. Da Silva,Daniel J. Fernandez,Colin J. McKinlay,Edward E. Lemmens,Chris S. Rae, Sudha Adusumilli,Ray Low, Srinivasa Bandi, Guna Kannan,W. Martin Kast,Samuel Deutsch,Ole A. Haabeth

Cancer Researchno. 6_Supplement (2024): 6536-6536

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Abstract 6725: NTX-470, a novel multispecific T cell engager expressed from mRNA targets PSMA and STEAP1 prostate cancer antigens to generate enhanced functional activity

Chris Rae, Sudha Adusumilli, Srinivasa Bandi,Shruti Lal, Pragyesh Dhungel, Kimmy Ferry, Shima Gholizadeh, Anushtha Sharma,Adrienne Sallets,Weiqun Liu,Evan McCartney-Melstad, Pei-Ken Hsu,Ray Low,Colin McKinlay,Meredith Leong,David Y. Oh,Lawrence Fong, Guna Kannan,Samuel Deutsch,Ole Haabeth

Cancer Researchno. 6_Supplement (2024): 6725-6725

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Local delivery of mRNA immunotherapy encoding HPV16 antigen, IL-12, and LIGHT/TNFSF14 results in superior immunogenicity and tumor clearance in a murine model of HPV16-driven cancer

Weiqun Liu,Diane M. Da Silva,Edward E. Lemmens,Colin J. McKinlay,Sangeeta Nath,Meredith L. Leong,Samuel Deutsch,W. Martin Kast,Ole Audun W. Haabeth

CANCER RESEARCHno. 7 (2023)

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Quantitative Analysis of The High-Yield Hydrolysis of Kelp by Laminarinase and Alginate Lyase

Taichi E. Takasuka,Hoon Kim,Kai Deng,Christopher M. Bianchetti,Kaho Yamashita,Emily T. Beebe,Lai F. Bergeman,Kirk A. Vander Meulen,Samuel Deutsch,John Ralph,Paul D. Adams,Trent R. Northen,Brian G. Fox

ChemBioChemno. 20 (2023)

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1359 NTX-0471, engineered multivalent SIRPa and bispecific SIRPa-antiCCR4 molecules demonstrate superior activity providing path for mRNA expressed in-vivo biologics

Weiqun Liu,Meredith Leong,Evan McCartney-Melstad,Colin McKinlay,Adrienne Sallets,Samuel Deutsch,Gunasekaran Kannan, Gowrisudha Adusumilli, Srinivasa Bandi,Shruti Lal,Ray Low,Ole Audun Haabeth, Pei-Ken Hsu, Kimmy Ferry, Anustha Sharma, Jenna Triplett

Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)

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Abstract 690: Modification of mRNA-encoded HPV16 antigens to include endolysosomal trafficking domains drives cross-presentation and results in superior in vivo and ex vivo antigen-specific responses

Weiqun Liu,Daniel Fernández,Colin J. McKinlay,Daniel O. Frimannsson,Meredith L. Leong,W. Martin Kast,Samuel Deutsch,Ole Audun Werner Haabeth

Cancer Researchno. 7_Supplement (2023): 690-690

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Abstract 5163: Local delivery of mRNA immunotherapy encoding HPV16 antigen, IL-12, and LIGHT/TNFSF14 results in superior immunogenicity and tumor clearance in a murine model of HPV16-driven cancer

Weiqun Liu,Diane M. Da Silva,Edward E. Lemmens,Colin J. McKinlay,Sangeeta Nath,Meredith L. Leong,Samuel Deutsch,W. Martin Kast,Ole Audun Werner Haabeth

Cancer Researchno. 7_Supplement (2023): 5163-5163

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Abstract LB346: Mapping of Shared Tumor Antigen Reactivity with Nanoparticle Encapsulated Mrna in Prostate Cancer Patients

Elena Montauti,Ole Haabeth,Chris Rae,Samuel Deutsch,Lawrence Fong,David Oh

Cancer Researchno. 8_Supplement (2023)

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