Sabine Sewing - Roche | 人才画像

基本信息

Career Trajectory

Bio

Sabine Sewing currently works at the Pharma Research and Early Development (pRED), Roche. Sabine does research in Physiology, Molecular Biology and Endocrinology with a focus on in vitro safety questions and single stranded oligonucleotides as novel therapeutic platform.

Research Interests

Papers共 60 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Investigating Discovery Strategies and Pharmacological Properties of Stereodefined Phosphorodithioate LNA Gapmers

Joerg Duschmale, Adrian Schaeublin,Erik Funder,Steffen Schmidt,Lukasz J. Kielpinski, Helle Nymark,Klaus Jensen,Troels Koch,Martina Duschmale,Erich Koller,Marianne Ravn Moller,Simone Schadt,Christophe Husser,Andreas Brink,Sabine Sewing,Tanja Minz,Jesper Wengel,Konrad Bleicher, Meiling Li

Molecular therapy Nucleic acids（2022）

Cited0Views0WOSBibtex

Combining in Vivo and Organotypic in Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator

Ramona Nudischer,Kasper Renggli,Cristina Bertinetti-Lapatki,Jean-Christophe Hoflack,Nicholas Flint,Sabine Sewing,Lykke Pedersen,Simone Schadt,Larry G. Higgins,Audrey Vardy,Barbara Lenz, Laurent Gand,Franziska Boess,Barbara M. Elcombe,Andreas Hierlemann,Adrian B. Roth

Toxicological sciences（2020）

Cited2Views0WOSBibtex

Refining LNA Safety Profile by Controlling Phosphorothioate Stereochemistry

Erik Daa Funder,Nanna Albaek,Annie Moisan,Sabine Sewing,Troels Koch

PLOS ONE（2020）

Cited11Views0WOSBibtex

GalNAc Conjugation Attenuates the Cytotoxicity of Antisense Oligonucleotide Drugs in Renal Tubular Cells

Sabine Sewing,Marcel Gubler,Régine Gérard,Blandine Avignon, Yasmin Mueller,Annamaria Braendli-Baiocco,Marielle Odin,Annie Moisan

Molecular Therapy - Nucleic Acids（2019）

Cited15Views0WOSBibtex

Assessing Single-Stranded Oligonucleotide Drug-Induced Effects in Vitro Reveals Key Risk Factors for Thrombocytopenia

Sabine Sewing,Adrian B. Roth,Michael Winter,Andreas Dieckmann,Cristina Bertinetti-Lapatki,Yann Tessier,Claudia McGinnis,Sylwia Huber,Erich Koller,Corinne Ploix,John C. Reed,Thomas Singer, Andreas Rathfuss

PloS oneno. 11 (2017): e0187574-e0187574

Cited31Views0WOSBibtex

Incretin-like effects of small molecule trace amine-associated receptor 1 agonists

Susanne Raab,Haiyan Wang,S Uhles,Nadine Cole,Ruben Alvarezsanchez,Basil Kunnecke,Christoph Ullmer,Hugues Matile,Marc Bedoucha,Roger Norcross,Nickki Ottawayparker,Diego Pereztilve, Karin Conde Knape,Matthias H Tschop,Marius C Hoener,Sabine Sewing

Molecular Metabolism（2016）

Cited78Views0WOSBibtex

Establishment of a Predictive in Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs

Sabine Sewing,Franziska Boess,Annie Moisan,Cristina Bertinetti-Lapatki,Tanja Minz, Maj Hedtjaern,Yann Tessier,Franz Schuler,Thomas Singer,Adrian B. Roth

PLoS ONE（2016）

Cited31Views0WOSBibtex

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