I joined the then Institute of Psychiatry in 1997 after starting my research career in agricultural research. I hold a BSc/MSc in Statistics from the University of Dortmund, Germany and previously worked in a project on agricultural sustainability at the Institute of Arable Crops Research - Rothamsted, Harpenden, followed by a PhD at the University of Nottingham in the areas of crop modelling and spatial statistics.
Since joining King’s I have been involved in applied health research with a focus on the development and evaluation of interventions to improve mental health. In addition to extensive experience in applying modern statistical methods in clinical or behavioural research I am involved with the development of relevant methodologies. My methodological research interest is in the field of causal inference, in particular for the evaluation of the efficacy and mechanisms of complex interventions in mental health.
As part of my affiliation with the King’s Clinical Trials Unit I serve as senior statistician on a number of trials. Within the department I lead the Causal Modelling and Evaluation research theme.
I have co-authored the books “A handbook of Statistical Analyses using SPSS” (Chapman and Hall/CRC, 2004) and “Cluster Analysis” (Wiley, 2001, 2011).
Research interests
Design and analysis of trials of complex interventions
Causal mediation analysis
Methods for process evaluation
Trial emulation using routinely collected data
Real-world evidence
Rapid evaluation methods including quasi-experimental methods
Individual participant data meta-mediation and moderation analyses