R. Lesche - Bayer AG, Nuvisan ICB GmbH

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Dual Targeting of the Androgen Receptor and PI3K/AKT/mTOR Pathways in Prostate Cancer Models Improves Antitumor Efficacy and Promotes Cell Apoptosis

Tatsuo Sugawara,Ekaterina Nevedomskaya, Simon Heller, Annika Boehme,Ralf Lesche,Oliver von Ahsen,Sylvia Gruenewald,Holly M. Nguyen,Eva Corey,Simon J. Baumgart,Victoria Georgi,Vera Puetter,Amaury Fernandez-Montalvan,James D. Vasta,Matthew B. Robers,Oliver Politz,Dominik Mumberg,Bernard Haendler

MOLECULAR ONCOLOGYno. 3 (2024): 726-742

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O31 How Useful Are the Mouse Models of Lupus for Clinical Research and Drug Testing

Fiona McDonald,Marta E Alarcón-Riquelme,Guillermo Barturen,Zuzanna Makowska,Jorge Kageyama,Anne Buttgereit,Ralf Lesche,Maria Morell, María Rivas-Torrubia

Lupus Science and Medicineno. Suppl 1 (2024)

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POS1391 UTILITY OF MOUSE MODELS OF LUPUS FOR CLINICAL RESEARCH AND DRUG TESTING

M. Rivas-Torrubia, M. Morell,Z. Makowska, J. Kageyama,A. Buttgereit,J. Lindblom, P. Cytometry Consortium,I. Parodis,L. Beretta,R. Lesche,F. Mcdonald,M. Alarcon-Riquelme,G. Barturen

Scientific Abstracts (2024)

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Velcrin Molecular Glues Induce Apoptosis in Glioblastomas with High PDE3A and SLFN12 Expression

Elisa Aquilanti,Silvia Goldoni,Andrew Baker, Kristyna Kotynkova, Sawyer Andersen, Vincent Bozinov,Galen F. Gao,Andrew D. Cherniack,Martin Lange,Ralf Lesche,Charlotte Kopitz,Philip Lienau,Timothy A. Lewis,Marine Garrido,Stefan Gradl,Henrik Seidel,Yuen-Yi Tseng,Keith L. Ligon,Patrick Y. Wen,Matthew Meyerson,Heidi Greulich

NEURO-ONCOLOGY ADVANCESno. 1 (2024)

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Pan-PI3K inhibition with copanlisib overcomes Treg- and M 2-TAM-mediated immune suppression and promotes anti-tumor immune responses

Simon Heller,Sarah Glaeske, Katja Gluske,Juliane Paul, Annika Böhme,Andreas Janzer,Helge Gottfried Roider,Anna Montebaur,Barbara Nicke,Ralf Lesche,Oliver von Ahsen,Oliver Politz,Ningshu Liu,Mátyás Gorjánácz

Clinical and Experimental Medicineno. 8 (2023): 5445-5461

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Supplementary Methods from Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

Maria Quanz,Eckhard Bender,Charlotte Kopitz,Sylvia Grünewald,Andreas Schlicker,Wolfgang Schwede,Ashley Eheim,Luisella Toschi,Roland Neuhaus,Carmen Richter,Joern Toedling,Claudia Merz,Ralf Lesche,Atanas Kamburov,Holger Siebeneicher,Marcus Bauser,Andrea Hägebarth

crossref（2023）

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Data from Genetic Background Controls Tumor Development in <i>Pten</i>-Deficient Mice

Dan Freeman,Ralf Lesche,Nathalie Kertesz, Shungyou Wang,Gang Li, Jing Gao,Matthias Groszer,Hilda Martinez-Diaz,Nora Rozengurt,George Thomas,Xin Liu,Hong Wu

crossref（2023）

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Abstract 6089: Identification of Novel YAP/TAZ Pathway Regulators in the Triple-Negative Breast Cancer Cell Line MDA-MB231 Using Single-Cell CRISPR Screening

Mareike Berlak,Zuzanna Makowska,Filippos Klironomos,Julia Kuehnlenz,Atanas Kamburov,Andreas Steffen,Martin Lange,Barbara Nicke,Ralf Lesche, Peter Staller,Charlotte Kopitz,Jan Naujoks

Cancer Researchno. 7_Supplement (2023): 6089-6089

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