My labor atory is interested in understanding the cellular and molecular mechanisms underlying host-microbe (both medical and plant pathogens) interactions. By using multiple cutting-edge technologies such as gene knockout, immunofluorescence confocal microscopy, transcriptomics, proteomics/phosphoproteomics, etc., we currently focus on genome-wide functional analysis of virulence-associated factors in Botrytis cinerea , the gray mold fungus that infects over 500 plant species and annually causes enormous economic losses worldwide, and dissection of molecular and/or biochemical mechanisms of the pathogenicity-associated factors that regulate the pathogen development and host infection as well as host immune responses.