Pietro Pichierri

I currently run an independent research group of eight people. Our group is involved in the investigation of mechanisms controlling genome stability in human cells during the S-phase of the cell cycle. These pathways are essential to prevent neoplastic transformation. We seek to elucidate the cellular pathways elicited by replication fork arrest and their inherent regulation to identify potential biomarkers and targets for cancer therapy. Moreover, we investigate on the relationship between replication stress and the pathogenesis of human genetic diseases.