Patrick Flagmeier - Dept Chem, Univ Cambridge

基本信息

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职业迁徙

个人简介

Research Fellow at the University of Cambridge Interested in tackling the development of therapies for the most challenging human disorders that the global population is facing.

研究兴趣

论文共 34 篇作者统计合作学者相似作者

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N-Terminal Acetylation of Α-Synuclein Slows Down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates

Rosie Bell,Rebecca J. Thrush,Marta Castellana-Cruz,Marc Oeller,Roxine Staats,Aishwarya Nene,Patrick Flagmeier,Catherine K. Xu,Sandeep Satapathy,Celine Galvagnion,Mark R. Wilson,Christopher M. Dobson,Janet R. Kumita,Michele Vendruscolo

Biochemistry（2022）

引用15浏览0WOS引用

Elongation Rate and Average Length of Amyloid Fibrils in Solution Using Isotope-Labelled Small-Angle Neutron Scattering

Ben J. Eves,James J. Doutch,Ann E. Terry, Han Yin,Martine Moulin,Michael Haertlein,V. Trevor Forsyth,Patrick Flagmeier,Tuomas P. J. Knowles,David M. Dias,Gudrun Lotze,Annela M. Seddon,Adam M. Squires

RSC Chemical Biology（2021）

引用5浏览0WOS引用

The Influence of Pathogenic Mutations in Α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils

Francesco Simone Ruggeri,Patrick Flagmeier,Janet R. Kumita,Georg Meisl,Dimitri Y. Chirgadze,Marie N. Bongiovanni,Tuomas P. J. Knowles,Christopher M. Dobson

ACS Nano（2020）

引用55浏览0WOS引用

Screening of Small Molecules Using the Inhibition of Oligomer Formation in Α-Synuclein Aggregation As a Selection Parameter

Roxine Staats,Thomas C. T. Michaels,Patrick Flagmeier,Sean Chia,Robert I. Horne,Johnny Habchi,Sara Linse,Tuomas P. J. Knowles,Christopher M. Dobson,Michele Vendruscolo

Communications chemistry（2020）

引用24浏览0WOSNATURE引用

Direct Measurement of Lipid Membrane Disruption Connects Kinetics and Toxicity of Aβ42 Aggregation

Patrick Flagmeier,Suman De,Thomas C. T. Michaels,Xiaoting Yang,Alexander J. Dear,Cecilia Emanuelsson,Michele Vendruscolo,Sara Linse,David Klenerman,Tuomas P. J. Knowles,Christopher M. Dobson

Nature structural & molecular biology（2020）

引用35浏览0WOS引用

Increased Secondary Nucleation Underlies Accelerated Aggregation Of The Four-Residue N-Terminally Truncated A Beta 42 Species A Beta 5-42

Tanja Weiffert,Georg Meisl,Patrick Flagmeier,Suman De,Christopher J. R. Dunning,Birgitta Frohm,Henrik Zetterberg,Kaj Blennow,Erik Portelius,David Klenerman,Christopher M. Dobson,Tuomas P. J. Knowles,Sara Linse

ACS Chem Neurosci（2019）

引用20浏览0WOS引用

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