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个人简介
Peter Vangheluwe, PhD’s research focuses on lysosomal transport systems that are implicated in Parkinson’s disease (PD) to understand the role of lysosomal dysfunction in PD. He’s appointed as Associate Professor at KU Leuven in Belgium, and is head of the Laboratory of Cellular Transport Systems. Using biochemical and molecular cell biology approaches, he characterizes new P-type transport ATPases that regulate ion homeostasis and lipid distribution in the cell. His team discovered the function of two orphan transporters that are genetically implicated in PD. He described that ATP13A2/PARK9 works as a lysosomal polyamine transporter, and that ATP10B operates as a lysosomal glucosylceramide exporter. These breakthroughs provide new insights into the molecular mechanisms of PD, and fuel a drug discovery pipeline for lysosomal transport modulators that runs together with pharmaceutical companies. He published >60 peer-reviewed publications and received two awards by the Queen Elisabeth Foundation for Neurosciences.
研究兴趣
论文共 153 篇作者统计合作学者相似作者
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Patrizia Agostinis,Francesca Rizzollo, Abril Escamilla-Ayala, Nicola Fattorelli, Natalia Lysiak, Sanket More, Lucia Barazzuol, Chris Van den Haute, Joris Van Asselberghs,David Nittner, Jonathan Coene, Vivek Venkataramani,Bernhard Michalke,Christine Gaillet, Tatiana Cañeque, Irwin Davidson, Steven Verhelst,Peter Vangheluwe, Tito Calì, Jean Christophe Marine,Raphaël Rodriguez, Julie Bonnereau
crossref(2024)
Aysha M. Bhojwani-Cabrera,Alicia Bautista-Garcia,Veronika E. Neubrand, Francisco A. Membrive-Jimenez,Mattia Bramini,David Martin-Oliva,Miguel A. Cuadros,Jose Luis Marin-Teva,Julio Navascues,Peter Vangheluwe,M. Rosario Sepulveda
GLIAno. 6 (2024): 1201-1214
CARDIOVASCULAR RESEARCHno. 7 (2024): 756-768
Ryo Tamura,Jialin Chen, Marijke De Jaeger, Jacqueline F Morris,David A Scott,Peter Vangheluwe,Loren L Looger
bioRxiv the preprint server for biology (2024)
Mujahid Azfar, Weiman Gao,Chris Van den Haute,Lin Xiao,Mawar Karsa,Ruby Pandher,Emma Ronca,Angelika Bongers, Ayu Karsa, Dayna Spurling, Xinyi Guo,Chelsea Mayoh,Mark R. Burns,Steven H.L. Verhelst,Murray D. Norris,Michelle Haber,Peter Vangheluwe,Klaartje Somers
biorxiv(2024)
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCHno. 1 (2024)
Neurogeneticsno. 4 (2024): 405-415
HUMAN MOLECULAR GENETICSno. 10 (2024): 930-930
Marine Houdou, Nathalie Jacobs, Jonathan Coene,Mujahid Azfar,Roeland Vanhoutte,Chris van den Haute,Jan Eggermont,Veronique Daniels,Steven H. L. Verhelst,Peter Vangheluwe
BIOMOLECULESno. 2 (2023)
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作者统计
#Papers: 153
#Citation: 3427
H-Index: 35
G-Index: 56
Sociability: 6
Diversity: 0
Activity: 1
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