His research interests focus on the pathophysiology and management of acute and chronic heart failure. He is co-author of more than 700 peer-reviewed papers with total number of citations: >120000, h-index=128; selected among Highly Cited Researchers by Thomson Reuters 2016, 2017, 2018, 2019, 2020.
In the years 2004-2019 professor Ponikowski served as a Member of Board of Heart Failure Association of the European Society of Cardiology (since 2004; in 2010-2012 as the President of Heart Failure Association), former President of Polish Cardiac Society (2015-2019).