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个人简介
Dr. Lazarov is a Professor of Neuroscience in the Department of Anatomy and Cell Biology at the University of Illinois at Chicago. Dr. Lazarov’s research focuses on the examination of molecular and cellular mechanisms of cognitive dysfunction in mouse models of familial Alzheimer’s disease (FAD) and in human tissue of individuals exhibiting mild cognitive impairments and Alzheimer’s disease. Her research focuses on the role of neurogenesis in hippocampal plasticity in aging- and Alzheimer’s disease-linked cognitive deterioration. Dr. Lazarov is a pioneer in the field of neurogenesis in Alzheimer’s disease. She was one the first to show that hippocampal neurogenesis is defective in FAD mice and may contribute to cognitive deficits characterizing the disease. In addition, she was one of the first to show that hippocampal neurogenesis persists throughout life in the human brain, albeit compromised in mild cognitive impairments and Alzheimer’s disease patients. In addition, studies at her lab examine the role of neural stem cells in cognitive failure in comorbidity, such as stroke or type-2-diabetes, as well as the role of endothelial and vascular factors that accelerate or contribute to the development of Alzheimer’s disease. Dr. Lazarov is the Director of the Alzheimer’s Disease and Related Dementia (ADRD) Training Program at UIC.
研究兴趣
论文共 102 篇作者统计合作学者相似作者
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Orly Lazarov,Ahmed Disouky,Mark Sanborn, Mostafa, K Sabitha,Aimee Schantz,Namhee Kim, Szymon Pawlowski,William Honer,David Bennett,Yi Zhou,C Keene,Mark Maienschein-Cline,Jalees Rehman
Research square (2024)
eneurono. 2 (2024): ENEURO.0496-23.2024
PROGRESS IN NEUROBIOLOGY (2024)
ENEUROno. 2 (2024)
Joseph W Leasure, Thi Mai, Avi Fogel, Pierina Danos, Li Wang,Mark A Sanborn,Zijing Ye, Young-Mee Kim, Xinhe Wang, Jennifer Flores, Muzamil Mushtaq,Peter T Toth,Sang-Ging Ong,Orly Lazarov,Jalees Rehman
biorxiv(2024)
Journal of Leukocyte Biology (2024)
Aashutosh U. Shetti, Abhirami Ramakrishnan,Liudmila Romanova,Wenping Li, Khanh Vo,Ipsita Volety,Ishara Ratnayake,Terilyn Stephen,Richard D. Minshall,Stephanie M. Cologna,Orly Lazarov
Brain a journal of neurologyno. 7 (2023): 3014-3028
Terilyn K L Stephen,Luis Aponte Cofresi, Elvis Quiroz,Kofi Owusu-Ansah, Yomna Ibrahim,Ellis Qualls, Jeffery Marshall,Wenping Li,Aashutosh Shetti,Jacqueline A Bonds,Richard D Minshall,Stephanie M Cologna,Orly Lazarov
bioRxiv the preprint server for biology (2023)
Frontiers in Aging Neuroscience (2023)
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作者统计
#Papers: 104
#Citation: 6845
H-Index: 37
G-Index: 61
Sociability: 6
Diversity: 3
Activity: 18
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