The research in my laboratory is mainly focused on (i) mitochondria and energy metabolism during neuronal activity, and (ii) the impact of microglia (brain macrophages) at different activation stages on neuronal activity and neurodegeneration. The experimental studies deal with activity patterns that are related to perception, attention and memory as well as epilepsy. We combine electrophysiological and fluorescence imaging recordings in hippocampal slice preparations from wild-type and transgenic animals.