Research Interests
Nasim’s research has focused on genetic susceptibility to breast cancer. She is presently investigating the value of genomic profiling for breast cancer risk stratification. The combined effect of multiple breast cancer susceptibility SNPs are represented in a polygenic risk score, which may be used for targeting breast cancer screening strategies, and risk reducing interventions to those at highest risk of developing breast cancer.

Nasim has also carried out work on risk modelling in BRCA1 and BRCA2 mutation carriers, studying tumour pathology in mutation carriers and estimating prospective breast cancer risks in BRCA1 and BRCA2 mutation carriers. Her PhD thesis involved incorporating tumour pathology information the genetic risk prediction algorithm BOADICEA. This work has now been used to extend the BOADICEA web interface, widely used by genetic counsellors and health practitioners for risk prediction.