She has been actively researching the effects of long-term cannabis use for more than 25 years and is now the most published researcher in the world on the topic of cannabis and the brain. Her primary area of expertise is in the long-term cognitive and neural effects of cannabis. She has used neuropsychological, psychophysiological and brain imaging techniques in her investigations of memory, cognition and brain structure and function in adult and adolescent cannabis users and people with schizophrenia and comorbid cannabis use.