Nancy Zhang

Department of Oncology Research Amgen Inc

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论文共 16 篇作者统计合作学者相似作者

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Phosphoinositide-3-kinase inhibitors: evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511

Brian A Lanman,Anthony B Reed,Victor J Cee,Fang-Tsao Hong,Liping H Pettus,Ryan P Wurz,Kristin L Andrews,Jian Jiang,John D McCarter,Erin L Mullady,Tisha San Miguel,Raju Subramanian,Ling Wang,Douglas A Whittington,Tian Wu,Leeanne Zalameda,Nancy Zhang,Andrew S Tasker,Paul E Hughes,Mark H Norman

Bioorganic & Medicinal Chemistry Letters（2014）

引用4浏览0WOS引用

Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method

Marc Payton,Toni Jun,William Wayne,Dongyin Yu,Raffi Manoukian,Grace Chung,Nancy Zhang,Ji-Rong Sun,Paula Kaplan-Lefko,Sheila Scully,Gwyneth Van,Robert Radinsky,Richard Kendall,Jonathan Oliner,Angela Coxon

LABORATORY INVESTIGATION（2014）

引用5浏览0WOSNATURE引用

Identification Of Amg 511 As A Selective Class I Phosphoinositide 3-Kinase Inhibitor

Ryan P. Wurz,Kristin L. Andrews,Yunxin Y. Bo,Shon K. Booker,Sean Caenepeel,Victor J. Cee,D'Angelo D. Noel,Daniel J. Freeman,Bradley J. Herberich,Fang-Tsao Hong,Claire L. M. Jackson,Jian Jiang,Brian A. Lanman,Longbin Liu,John D. Mccarter,Erin L. Mullady,Nobuko Nishimura,Liping H. Pettus,Anthony B. Reed,Tisha San Miguel,Adrian L. Smith,Markian M. Stec,Seifu Tadesse,Andrew S. Tasker,Divesh Aidasani,Xiaochun Zhu,Raju Subramanian,Nuria A. Tamayo,Ling Wang,Douglas A. Whittington,Bin Wu,Tian Wu,Kevin Yang,Leeanne Zalameda,Nancy Zhang,Paul E. Hughes,Mark H. Norman

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2013）

引用0浏览0引用

Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511

Mark H Norman,Kristin L Andrews,Yunxin Y Bo,Shon K Booker,Sean Caenepeel,Victor J Cee,Noel D D'Angelo,Daniel J Freeman,Bradley J Herberich,Fang-Tsao Hong,Claire L M Jackson,Jian Jiang,Brian A Lanman,Longbin Liu,John D McCarter,Erin L Mullady,Nobuko Nishimura,Liping H Pettus,Anthony B Reed,Tisha San Miguel,Adrian L Smith,Markian M Stec,Seifu Tadesse,Andrew Tasker,Divesh Aidasani,Xiaochun Zhu,Raju Subramanian,Nuria A Tamayo,Ling Wang,Douglas A Whittington,Bin Wu,Tian Wu,Ryan P Wurz,Kevin Yang,Leeanne Zalameda,Nancy Zhang,Paul E Hughes

JOURNAL OF MEDICINAL CHEMISTRY（2012）

引用48浏览0WOS引用

Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511 (vol 55, pg 7796, 2012)

Mark H. Norman,Kristin L. Andrews,Yunxin Y. Bo,Shon K. Booker,Sean Caenepeel,Victor J. Cee,Noel D. D'Angelo,Daniel J. Freeman,Bradley J. Herberich,Fang-Tsao Hong,Claire L. M. Jackson,Jian Jiang,Brian A. Lanman,Longbin Liu,John D. McCarter,Erin L. Mullady,Nobuko Nishimura,Liping H. Pettus,Anthony B. Reed,Tisha San Miguel,Adrian L. Smith,Markian M. Stec,Seifu Tadesse,Andrew Tasker,Divesh Aidasani,Xiaochun Zhu,Raju Subramanian,Nuria A. Tamayo,Ling Wang,Douglas A. Whittington,Bin Wu,Tian Wu,Ryan P. Wurz,Kevin Yang,Leeanne Zalameda,Nancy Zhang,Paul E. Hughes

JOURNAL OF MEDICINAL CHEMISTRY（2012）

引用2浏览0引用

Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases

Adrian L Smith,Noel D D'Angelo,Yunxin Y Bo,Shon K Booker,Victor J Cee,Brad Herberich,Fang-Tsao Hong,Claire L M Jackson,Brian A Lanman,Longbin Liu,Nobuko Nishimura,Liping H Pettus,Anthony B Reed,Seifu Tadesse,Nuria A Tamayo,Ryan P Wurz,Kevin Yang,Kristin L Andrews,Douglas A Whittington,John D McCarter,Tisha San Miguel,Leeanne Zalameda,Jian Jiang,Raju Subramanian,Erin L Mullady,Sean Caenepeel,Daniel J Freeman,Ling Wang,Nancy Zhang,Tian Wu,Paul E Hughes,Mark H Norman

JOURNAL OF MEDICINAL CHEMISTRY（2012）

引用50浏览0WOS引用

Identification Of A Novel Series Of Highly Potent And Selective Inhibitors Of The Class I Phosphatidylinositol 3-Kinases For Treatment Of Cancer

Fang-Tsao Hong,Adrian L. Smith,Noel D. D'Angelo,Yunxin Y. Bo,Shon K. Booker,Victor J. Cee,Brad Herberich,Claire L. M. Jackson,Brian A. Lanman,Longbin Liu,Nobuko Nishimura,Liping H. Pettus,Anthony B. Reed,Seifu Tadesse,Nuria A. Tamayo,Ryan P. Wurz,Kevin Yang,Kristin L. Andrews,Douglas A. Whittington,John D. Mccarter,Tisha San Miguel,Leeanne Zalameda,Jian Jiang,Raju Subramanian,Erin L. Mullady,Sean Caenepeel,Daniel J. Freeman,Ling Wang,Nancy Zhang,Tian Wu,Paul E. Hughes,Mark H. Norman

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2012）

引用0浏览0引用

Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold

Ryan P Wurz,Longbin Liu,Kevin Yang,Nobuko Nishimura,Yunxin Bo,Liping H Pettus,Sean Caenepeel,Daniel J Freeman,John D McCarter,Erin L Mullady,Tisha San Miguel,Ling Wang,Nancy Zhang,Kristin L Andrews,Douglas A Whittington,Jian Jiang,Raju Subramanian,Paul E Hughes,Mark H Norman

Bioorganic & Medicinal Chemistry Letters（2012）

引用26浏览0WOS引用

Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives

Nobuko Nishimura,Aaron Siegmund,Longbin Liu,Kevin Yang,Marian C Bryan,Kristin L Andrews,Yunxin Bo,Shon K Booker,Sean Caenepeel,Daniel Freeman,Hongyu Liao,John McCarter,Erin L Mullady,Tisha San Miguel,Raju Subramanian,Nuria Tamayo,Ling Wang,Douglas A Whittington,Leeanne Zalameda,Nancy Zhang,Paul E Hughes,Mark H Norman

JOURNAL OF MEDICINAL CHEMISTRY（2011）

引用64浏览0WOS引用

Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors

Noel D D'Angelo,Tae-Seong Kim,Kristin Andrews,Shon K Booker,Sean Caenepeel,Kui Chen,Derin D'Amico,Dan Freeman,Jian Jiang,Longbin Liu,John D McCarter,Tisha San Miguel,Erin L Mullady,Michael Schrag,Raju Subramanian,Jin Tang, Robert C Wahl,Ling Wang,Douglas A Whittington,Tian Wu,Ning Xi,Yang Xu,Peter Yakowec,Kevin Yang,Leeanne P Zalameda,Nancy Zhang,Paul Hughes,Mark H Norman

JOURNAL OF MEDICINAL CHEMISTRY（2011）

引用106浏览0WOS引用

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作者统计

#Papers: 16

#Citation: 917

H-Index: 8

G-Index: 11

Sociability: 5

Diversity: 2

Activity: 0

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