Hughes Paul E - Department of Oncology Research, Amgen Inc.

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Papers共 129 篇Author StatisticsCo-AuthorSimilar Experts

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Abstract 5825: Non-genetic Determinants Driving the Evolutional Trajectories of Drug-Tolerant-persisters in KRAS Non-small Cell Lung Cancer

Chendi Li, Christopher J. Graser,Qian Qin, Anahita Nimbalkar, Usman Syed,Barbara Karakyriakou,Sarah Clark,Anne Y. Saiki,Paul E. Hughes,Christopher Ott,Luca Pinello,Franziska Michor,Aaron Hata

CANCER RESEARCHno. 6 (2024)

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Therapeutic Targeting of the KIF18A Motor Protein in Cancers with Chromosomal Instability

Marc Payton,Paul E. Hughes

NATURE CANCER (2024)

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Weakened APC/C Activity at Mitotic Exit Drives Cancer Vulnerability to KIF18A Inhibition

Colin R Gliech,Zhong Y Yeow,Daniel Tapias-Gomez,Yuchen Yang, Zhaoyu Huang,Andréa E Tijhuis,Diana CJ Spierings,Floris Foijer,Grace Chung,Nuria Tamayo, Zahra Bahrami-Nejad, Patrick Collins,Thong T Nguyen, Andres Plata Stapper,Paul E Hughes,Marc Payton,Andrew J Holland

The EMBO Journalno. 5 (2024): 666-694

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AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers

Brian Belmontes, Katherine K Slemmons, Chun Su,Siyuan Liu,Antonia N Policheni,Jodi Moriguchi,Hong Tan, Fang Xie, Daniel Andrew Aiello,Yajing Yang, Raul Lazaro,Famke Aeffner,Matthew G Rees,Melissa M Ronan,Jennifer A Roth,Mikkel Vestergaard,Sanne Cowland, Jan Andersson,Ian Sarvary,Qing Chen, Pooja Sharma,Patricia Lopez,Nuria Tamayo,Liping H Pettus,Sudipa Ghimire-Rijal,Susmith Mukund,Jennifer R Allen,Jason DeVoss,Angela Coxon,Jordi Rodon,Francois Ghiringhelli,Nicolas Penel,Hans Prenen,Sanne Glad,Chen-Hua Chuang, Kiana Keyvanjah,Danielle M Townsley, John R Butler,Matthew P Bourbeau,Sean Caenepeel,Paul E Hughes

Cancer discovery (2024)

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Abstract 3867: Chromatin Modification Driving Sub-Clonal Resistance to KRAS G12C Combination Therapies in KRAS Mutant Non-Small Cell Lung Cancer

Chendi Li,Qian Qin,Mohammed Usman Syed, Anahita Nimbalkar,Barbara Karakyriakou,Sarah E. Clark,Anne Y. Saiki,Paul E. Hughes, Chris Ott,Luca Pinello,Aaron N. Hata

CANCER RESEARCHno. 7 (2023)

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