Lin Min-Hwa Jasmine

Department of Neuroscience and Department of Biologics, Amgen, Inc

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论文共 34 篇作者统计合作学者相似作者

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Engineering Na V 1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics

Justin K Murray,Bin Wu,Christopher M Tegley,Thomas E Nixey,James R Falsey,Brad Herberich,Li Yin,Kelvin Sham,Jason Long,Jennifer Aral,Yuan Cheng,Chawita Netirojjanakul,Liz Doherty,Charles Glaus,Tayo Ikotun,Hongyan Li,Linh Tran,Marcus Soto,Hossein Salimi-Moosavi,Joseph Ligutti,Shanti Amagasu,Kristin L Andrews,Xuhai Be,Min-Hwa Jasmine Lin,Robert S Foti,Christopher P Ilch,Beth Youngblood,Thomas J Kornecook, Margaret Karow,Kenneth W Walker,Bryan D Moyer,Kaustav Biswas,Les P Miranda

ACS Chem. Biol.（2019）

引用14浏览0WOS引用

Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Bin Wu,Justin K. Murray,Kristin L. Andrews,Kelvin Sham,Jason Long,Jennifer Aral,Joseph Ligutti,Shanti Amagasu,Dong Liu,Anruo Zou,Xiaoshan Min, Zhulun Wang,Christopher P. Ilch,Thomas J. Kornecook,Min-Hwa Jasmine Lin,Xuhai Be,Les P. Miranda,Bryan D. Moyer,Kaustav Biswas

Journal of Medicinal Chemistry（2018）

引用25浏览0WOS引用

Sulfonamides As Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities

Matthew M. Weiss,Thomas A. Dineen,Isaac E. Marx, Steven Altmann,Alessandro Boezio,Howard Bregman,Margaret Chu-Moyer,Erin F. DiMauro,Elma Feric Bojic,Robert S. Foti,Hua Gao,Russell Graceffa,Hakan Gunaydin,Angel Guzman-Perez,Hongbing Huang,Liyue Huang,Michael Jarosh,Thomas Kornecook,Charles R. Kreiman,Joseph Ligutti,Daniel S. La,Min-Hwa Jasmine Lin,Dong Liu,Bryan D. Moyer,Hanh N. Nguyen,Emily A. Peterson,Paul E. Rose,Kristin Taborn,Beth D. Youngblood,Violeta Yu,Robert T. Fremeau

Journal of medicinal chemistryno. 14 (2017): 5969-5989

引用43浏览0WOS引用

Sulfonamides As Selective Na(V)1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (Am-0466) That Affords Robust in Vivo Activity

Russell F. Graceffa,Alessandro A. Boezio,Jessica Able, Steven Altmann,Loren M. Berry,Christiane Boezio,John R. Butler,Margaret Chu-Moyer,Melanie Cooke,Erin F. DiMauro,Thomas A. Dineen,Elma Feric Bojic,Robert S. Foti,Robert T. Fremeau,Angel Guzman-Perez,Hua Gao,Hakan Gunaydin,Hongbing Huang,Liyue Huang,Christopher Ilch,Michael Jarosh,Thomas Kornecook,Charles R. Kreiman,Daniel S. La,Joseph Ligutti,Benjamin C. Milgram,Min-Hwa Jasmine Lin,Isaac E. Marx,Hanh N. Nguyen,Emily A. Peterson,Gwen Rescourio,John Roberts,Laurie Schenkel,Roman Shimanovich,Brian A. Sparling,John Stellwagen,Kristin Taborn,Karina R. Vaida,Jean Wang, John Yeoman,Violeta Yu,Dawn Zhu,Bryan D. Moyer,Matthew M. Weiss

JOURNAL OF MEDICINAL CHEMISTRY（2017）

引用58浏览0WOS引用

Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates

Kaustav Biswas,Thomas E Nixey,Justin K Murray,James R Falsey,Li Yin,Hantao Liu,Jacinthe Gingras,Brian E Hall,Brad Herberich,Jerry Ryan Holder,Hongyan Li,Joseph Ligutti,Min-Hwa Jasmine Lin,Dong Liu,Brian D Soriano,Marcus Soto,Linh Tran,Christopher M Tegley, Anrou Zou,Kannan Gunasekaran,Bryan D Moyer,Liz Doherty,Les P Miranda

ACS chemical biology（2017）

引用25浏览0WOS引用

Sulfonamides As Selective Na(V)1.7 Inhibitors: Optimizing Potency And Pharmacokinetics To Enable In Vivo Target Engagement (Vol 7, Pg 1062, 2016)

Isaac E. Marx,Thomas A. Dineen,Jessica Able,Christiane Bode,Howard Bregman,Margaret Chu-Moyer,Erin F. Dimauro,Bingfan Du,Robert S. Foti,Robert T. Fremeau,Hua Gao,Hakan Gunaydin,Brian E. Hall,Liyue Huang,Thomas Kornecook,Charles R. Kreiman,Daniel S. La,Joseph Ligutti,Min-Hwa Jasmine Lin,Dong Liu,Jeff S. Mcdermott,Bryan D. Moyer,Hanh N. Nguyen,Emily A. Peterson,Jonathan T. Roberts,Paul Rose,Jean Wang,Beth D. Youngblood,Violeta Yu,Matthew M. Weiss

ACS MEDICINAL CHEMISTRY LETTERSno. 3 (2017)

引用0浏览0引用

The Discovery of Benzoxazine Sulfonamide Inhibitors of Na V 1.7: Tools That Bridge Efficacy and Target Engagement

Daniel S. La,Emily A. Peterson,Christiane Bode,Alessandro A. Boezio,Howard Bregman,Margaret Y. Chu-Moyer,James Coats,Erin F. DiMauro,Thomas A. Dineen,Bingfan Du,Hua Gao,Russell Graceffa,Hakan Gunaydin,Angel Guzman-Perez,Robert Fremeau,Xin Huang,Christopher Ilch,Thomas J. Kornecook,Charles Kreiman,Joseph Ligutti,Min-Hwa Jasmine Lin,Jeff S. McDermott,Isaac Marx,David J. Matson,Stefan I. McDonough,Bryan D. Moyer,Hanh Nho Nguyen,Kristin Taborn,Violeta Yu,Matthew M. Weiss

Bioorganic & medicinal chemistry letters（2017）

引用18浏览0WOS引用

Correction to “sulfonamides As Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement”

Isaac E. Marx,Thomas A. Dineen,Jessica Able,Christiane Bode,Howard Bregman,Margaret Y. Chu‐Moyer,Erin F. DiMauro,Bingfan Du, R. Foti,Robert T. Fremeau,Hua Gao,Hakan Günaydın,Brian E. Hall,Liyue Huang,Thomas Kornecook,Charles R. Kreiman,Daniel S. La,Joseph Ligutti,Min-Hwa Jasmine Lin,Dong Liu,Jeff S. McDermott,Bryan D. Moyer,Hanh Nho Nguyen,Emily A. Peterson,Jonathan Roberts,Paul Rose,Jean Wang,Beth D. Youngblood,Violeta Yu,Matthew M. Weiss

ACS medicinal chemistry letters（2017）

引用32浏览0引用

Discovery of (R)-6-(1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity

Alessandro A Boezio,Katrina W Copeland,Karen Rex,Brian K Albrecht,David Bauer,Steven F Bellon,Christiane Boezio,Martin A Broome,Deborah Choquette,Angela Coxon,Isabelle Dussault,Satoko Hirai,Richard Lewis,Min-Hwa Jasmine Lin,Julia Lohman,Jingzhou Liu,Emily A Peterson, Michele Potashman,Roman Shimanovich,Yohannes Teffera,Douglas A Whittington,Karina R Vaida,Jean-Christophe Harmange

JOURNAL OF MEDICINAL CHEMISTRY（2016）

引用31浏览0WOS引用

Sulfonamides As Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement

Isaac E. Marx,Thomas A. Dineen,Jessica Able,Christiane Bode,Howard Bregman,Margaret Y. Chu‐Moyer,Erin F. DiMauro,Bingfan Du, R. Foti,Robert T. Fremeau,Hua Gao,Hakan Günaydın,Brian E. Hall,Liyue Huang,Thomas Kornecook,Charles R. Kreiman,Daniel S. La,Joseph Ligutti,Min-Hwa Jasmine Lin,Dong Liu,Jeff S. McDermott,Bryan D. Moyer,Emily A. Peterson,Jonathan Roberts,Paul Rose,Jean Wang,Beth D. Youngblood,Violeta Yu,Matthew M. Weiss

ACS medicinal chemistry letters（2016）

引用39浏览0引用

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作者统计

#Papers: 34

#Citation: 586

H-Index: 15

G-Index: 22

Sociability: 6

Diversity: 2

Activity: 0

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