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个人简介
The research in the Taipale lab is organized around two central themes: technology development in functional genomics and proteomics and the organization and function of the human protein homeostasis network in health and disease. Individual projects in the lab are very diverse, spanning bacterial toxins to transcriptional regulation to rare disorders to chaperone/client interactions. But despite this diversity, all projects share common features. We take advantage of – or develop new – large-scale systematic ‘omics’ methods and use them as an entry point to understand biological processes. In particular, we aim to understand these processes through the lens of interactions between molecules – be they proteins, DNA, RNA, or small-molecule compounds. Another similarity is that all projects involve close collaborations with other research groups. Not only are collaborations a lot of fun, but they also allow us to tackle the inevitable tradeoff between the breadth and depth of expertise.
研究兴趣
论文共 71 篇作者统计合作学者相似作者
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Heather A Baker,Jonathan P Bernardini,Veronika Csizmok, Angel Madero, Shriya Kamat, Hailey Eng,Jessica Lacoste, Faith Yeung,Sophie Comyn,Gaetano Calabrese,Mikko Taipale,Brian Raught,
biorxiv(2024)
Juline Poirson, Hanna Cho, Akashdeep Dhillon, Shahan Haider, Ahmad Zoheyr Imrit,Mandy Hiu Yi Lam,Nader Alerasool,Jessica Lacoste, Lamisa Mizan,Cassandra Wong,Anne-Claude Gingras,Daniel Schramek,
Natureno. 8009 (2024): 1-9
David M. Ichikawa,Osama Abdin,Nader Alerasool,Manjunatha Kogenaru, April L. Mueller,Han Wen,David O. Giganti,Gregory W. Goldberg, Samantha Adams,Jeffrey M. Spencer, Rozita Razavi,Satra Nim,
NATURE BIOTECHNOLOGYno. 8 (2023): 1117-1129
Molecular cellno. 6 (2023): 974-993.e15
Molecular oncologyno. 9 (2023): 1803-1820
Jessica Lacoste,Marzieh Haghighi,Shahan Haider,Zhen-Yuan Lin, Dmitri Segal,Chloe Reno,Wesley Wei Qian, Xueting Xiong, Hamdah Shafqat-Abbasi,Pearl V Ryder,Rebecca Senft,Beth A Cimini,
bioRxiv : the preprint server for biology (2023)
biorxiv(2022)
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